A potential water-soluble ytterbium-based porphyrin–cyclen dual bio-probe for Golgi apparatus imaging and photodynamic therapy

Jing Xiang Zhang*, Hongguang Li, Chi Fai Chan, Rongfeng Lan, Wai Lun Chan, Ga Lai Law, Rick W K WONG, Ka-Leung WONG

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)

Abstract

An amphiphilic water-soluble ytterbium complex which is photo-selective, functional and Golgi apparatus specific has been designed as a responsive dual probe capable of sensitizing emission within the biological window (660 and 750 nm), generating the singlet oxygen (ΦΔ = 0.45) and triggering local cell damage only upon exposure to visible and near-infrared laser excitation.

Original languageEnglish
Pages (from-to)9646-9648
Number of pages3
JournalChemical Communications
Volume48
Issue number77
DOIs
Publication statusPublished - 29 Aug 2012

Scopus Subject Areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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