A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges

Quan-Bin Han, Ling Yang, Yu-Lin Wang, Chun-Feng Qiao, Jing-Zheng Song, Han-Dong Sun, Hong-Xi Xu

Research output: Contribution to journalJournal articlepeer-review

44 Citations (Scopus)

Abstract

Two new polyprenylated xanthone epimers were isolated from gamboges of Garcinia hanburyi, and identified by detailed spectroscopic analysis as 30-hydroxygambogic acid (2a) and its (2S)-epimer 30-hydroxyepigambogic acid (2b). Both compounds exhibited significant cytotoxicities against the human leukemia K562/S and the corresponding doxorubicin-resistant K562/R cell lines (Table 2).
Original languageEnglish
Pages (from-to)101-105
JournalChemistry and Biodiversity
Volume3
Issue number1
DOIs
Publication statusPublished - Jan 2006
Externally publishedYes

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