A Novel Asymmetric ent-Kaurane Dimer from Isodon rubescens var. rubescens

Quan Bin Han, Zhen Dan He, Chun Feng Qiao, Hong Xi Xu, Han Dong Sun*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

7 Citations (Scopus)


A novel asymmetric ent-kaurane dimer, xindongnin P (1), was isolated from Isodon rubescens var. rubescens. Its structure was elucidated by detailed spectroscopic analysis. Compound 1 contains a tetrahydrofuran moiety whose formation leads to inversion of configuration at C(16). This differentiates 1 from known related dimers, which were isolated before from the Isodon genus. A likely biogenetic pathway from the alleged monomer precursor 3 is proposed.

Original languageEnglish
Pages (from-to)817-821
Number of pages5
JournalHelvetica Chimica Acta
Issue number4
Publication statusPublished - 19 Apr 2005

Scopus Subject Areas

  • Catalysis
  • Biochemistry
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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