A Novel Asymmetric ent-Kaurane Dimer from Isodon rubescens var. rubescens

Quan Bin Han; Zhen Dan He; Chun Feng Qiao; Hong Xi Xu; Han Dong Sun

doi:10.1002/hlca.200590059

A Novel Asymmetric ent-Kaurane Dimer from Isodon rubescens var. rubescens

Quan Bin Han, Zhen Dan He, Chun Feng Qiao, Hong Xi Xu, Han Dong Sun^*

^*Corresponding author for this work

Chinese Medicine - Teaching and Research Division

Research output: Contribution to journal › Journal article › peer-review

7 Citations (Scopus)

Abstract

A novel asymmetric ent-kaurane dimer, xindongnin P (1), was isolated from Isodon rubescens var. rubescens. Its structure was elucidated by detailed spectroscopic analysis. Compound 1 contains a tetrahydrofuran moiety whose formation leads to inversion of configuration at C(16). This differentiates 1 from known related dimers, which were isolated before from the Isodon genus. A likely biogenetic pathway from the alleged monomer precursor 3 is proposed.

Original language	English
Pages (from-to)	817-821
Number of pages	5
Journal	Helvetica Chimica Acta
Volume	88
Issue number	4
DOIs	https://doi.org/10.1002/hlca.200590059
Publication status	Published - 19 Apr 2005

Scopus Subject Areas

Catalysis
Biochemistry
Drug Discovery
Physical and Theoretical Chemistry
Organic Chemistry
Inorganic Chemistry

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title = "A Novel Asymmetric ent-Kaurane Dimer from Isodon rubescens var. rubescens",

abstract = "A novel asymmetric ent-kaurane dimer, xindongnin P (1), was isolated from Isodon rubescens var. rubescens. Its structure was elucidated by detailed spectroscopic analysis. Compound 1 contains a tetrahydrofuran moiety whose formation leads to inversion of configuration at C(16). This differentiates 1 from known related dimers, which were isolated before from the Isodon genus. A likely biogenetic pathway from the alleged monomer precursor 3 is proposed.",

author = "Han, {Quan Bin} and He, {Zhen Dan} and Qiao, {Chun Feng} and Xu, {Hong Xi} and Sun, {Han Dong}",

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AU - Han, Quan Bin

AU - He, Zhen Dan

AU - Qiao, Chun Feng

AU - Xu, Hong Xi

AU - Sun, Han Dong

PY - 2005/4/19

Y1 - 2005/4/19

N2 - A novel asymmetric ent-kaurane dimer, xindongnin P (1), was isolated from Isodon rubescens var. rubescens. Its structure was elucidated by detailed spectroscopic analysis. Compound 1 contains a tetrahydrofuran moiety whose formation leads to inversion of configuration at C(16). This differentiates 1 from known related dimers, which were isolated before from the Isodon genus. A likely biogenetic pathway from the alleged monomer precursor 3 is proposed.

AB - A novel asymmetric ent-kaurane dimer, xindongnin P (1), was isolated from Isodon rubescens var. rubescens. Its structure was elucidated by detailed spectroscopic analysis. Compound 1 contains a tetrahydrofuran moiety whose formation leads to inversion of configuration at C(16). This differentiates 1 from known related dimers, which were isolated before from the Isodon genus. A likely biogenetic pathway from the alleged monomer precursor 3 is proposed.

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U2 - 10.1002/hlca.200590059

DO - 10.1002/hlca.200590059

M3 - Journal article

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JO - Helvetica Chimica Acta

JF - Helvetica Chimica Acta

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ER -

A Novel Asymmetric ent-Kaurane Dimer from Isodon rubescens var. rubescens

Abstract

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