A new pyranoxanthone from the stems of Calophyllum membranaceum

Guang Ying Chen; Guo Yuan Zhu; Chang Ri Han; Jun Zhao; Xiao Ping Song; David W F FONG

doi:10.3998/ark.5550190.0009.d27

A new pyranoxanthone from the stems of Calophyllum membranaceum

Guang Ying Chen, Guo Yuan Zhu, Chang Ri Han^*, Jun Zhao, Xiao Ping Song, David W F FONG

^*Corresponding author for this work

School of Chinese Medicine

Research output: Contribution to journal › Journal article › peer-review

10 Citations (Scopus)

Abstract

A new pyranoxanthone, membraxanthone A (1) has been isolated from the ethanol extract of the stem of Calophyllum membranaceum, together with three known pyranoxanthones, nigrolineaxanthone W (2), calophinone (3) and caloxanthone I (4), and three known triterpenoids, friedelin (5), canophyllol (6) and canophyllic acid (7). Their structures were elucidated on the basis of chemical evidence and intensive spectroscopic analysis including HRESI-MS, 1D- and 2D-NMR. All of the compounds were isolated from this plant for the first time. These xanthones showed no activities towards human cancer cell lines KB, BC-1 and NCI-4460.

Original language	English
Pages (from-to)	249-254
Number of pages	6
Journal	Arkivoc
Volume	2008
Issue number	13
DOIs	https://doi.org/10.3998/ark.5550190.0009.d27
Publication status	Published - 17 Jul 2008

User-Defined Keywords

Calophyllum membranaceum
Guttiferae
Membraxanthone A
Pyranoxanthones
Triterpenoids

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3998/ark.5550190.0009.d27

Cite this

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title = "A new pyranoxanthone from the stems of Calophyllum membranaceum",

abstract = "A new pyranoxanthone, membraxanthone A (1) has been isolated from the ethanol extract of the stem of Calophyllum membranaceum, together with three known pyranoxanthones, nigrolineaxanthone W (2), calophinone (3) and caloxanthone I (4), and three known triterpenoids, friedelin (5), canophyllol (6) and canophyllic acid (7). Their structures were elucidated on the basis of chemical evidence and intensive spectroscopic analysis including HRESI-MS, 1D- and 2D-NMR. All of the compounds were isolated from this plant for the first time. These xanthones showed no activities towards human cancer cell lines KB, BC-1 and NCI-4460.",

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author = "Chen, {Guang Ying} and Zhu, {Guo Yuan} and Han, {Chang Ri} and Jun Zhao and Song, {Xiao Ping} and FONG, {David W F}",

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T1 - A new pyranoxanthone from the stems of Calophyllum membranaceum

AU - Chen, Guang Ying

AU - Zhu, Guo Yuan

AU - Han, Chang Ri

AU - Zhao, Jun

AU - Song, Xiao Ping

AU - FONG, David W F

PY - 2008/7/17

Y1 - 2008/7/17

N2 - A new pyranoxanthone, membraxanthone A (1) has been isolated from the ethanol extract of the stem of Calophyllum membranaceum, together with three known pyranoxanthones, nigrolineaxanthone W (2), calophinone (3) and caloxanthone I (4), and three known triterpenoids, friedelin (5), canophyllol (6) and canophyllic acid (7). Their structures were elucidated on the basis of chemical evidence and intensive spectroscopic analysis including HRESI-MS, 1D- and 2D-NMR. All of the compounds were isolated from this plant for the first time. These xanthones showed no activities towards human cancer cell lines KB, BC-1 and NCI-4460.

AB - A new pyranoxanthone, membraxanthone A (1) has been isolated from the ethanol extract of the stem of Calophyllum membranaceum, together with three known pyranoxanthones, nigrolineaxanthone W (2), calophinone (3) and caloxanthone I (4), and three known triterpenoids, friedelin (5), canophyllol (6) and canophyllic acid (7). Their structures were elucidated on the basis of chemical evidence and intensive spectroscopic analysis including HRESI-MS, 1D- and 2D-NMR. All of the compounds were isolated from this plant for the first time. These xanthones showed no activities towards human cancer cell lines KB, BC-1 and NCI-4460.

KW - Calophyllum membranaceum

KW - Guttiferae

KW - Membraxanthone A

KW - Pyranoxanthones

KW - Triterpenoids

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DO - 10.3998/ark.5550190.0009.d27

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SN - 1551-7012

VL - 2008

SP - 249

EP - 254

JO - Arkivoc

JF - Arkivoc

IS - 13

ER -

A new pyranoxanthone from the stems of Calophyllum membranaceum

Abstract

User-Defined Keywords

UN SDGs

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