A new liquid chromatography–fluorescence method for determination of perfluorooctanesulphonyl fluoride upon derivatisation with 1-naphthol

Xiangpeng Meng, Zhi Tang, Qinghua Li, Charlie Li, Zongwei CAI*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Perfluorooctanesulphonyl fluoride (PFOSF), as a main precursor of perfluorooctanesulphonate (PFOS) that is ubiquitous in the environment, has been released to the environment with substantial quantity. Determination of PFOSF presents significant analytical challenges for using liquid chromatography with UV (LC–UV) and fluorescence detection (LC–FLD) due to the lack of chromophore in the molecular structure. In this study, a new method was developed by derivatising PFOSF with 1-naphthol to form 1-naphthylperfluorooctanesulphonate (NPFOS), which allowed rapid qualitative and quantitative analysis using LC–UV and LC–FLD. The derivatising product was confirmed from the analyses by proton nuclear magnetic resonance and quadrupole–time of flight mass spectrometry. The LC–FLD method demonstrated good linearity in the NPFOS concentration range from 20 pg µL−1 to 20 ng µL 1 with a correlation coefficient better than 0.999, with the instrument detection limit of 1.5 pg µL 1.

Original languageEnglish
Pages (from-to)1388-1393
Number of pages6
JournalInternational Journal of Environmental Analytical Chemistry
Volume94
DOIs
Publication statusPublished - 8 Dec 2014

Scopus Subject Areas

  • Analytical Chemistry
  • Environmental Chemistry
  • Water Science and Technology
  • Waste Management and Disposal
  • Soil Science
  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

User-Defined Keywords

  • derivatisation
  • LC–FLD
  • perfluorooctanesulphonyl fluoride
  • POPs

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