A new fungicide produced by a Streptomyces sp. GAAS7310

Guangying Chen, Birun Lin, Yongcheng Lin*, Fengchun Xie, Wen Lu, David W F FONG

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

35 Citations (Scopus)


Directed bioassay guided fraction led to a new macrodiolide antimycin A17 (1), isolated from a Streptomyces sp. GAAS7310, which showed significant antimicrobial activity against eleven fungal species, including Curvularia lunata (Wakker) Boed, Rhizopus nigrtcans Ehrb and Colletotrichum nigrum EL. et Halst. The structure was unambiguously established by interpretation of 1D and 2D NMR data and comparison with the known antimycin A1a.

Original languageEnglish
Pages (from-to)519-522
Number of pages4
JournalJournal of Antibiotics
Issue number8
Publication statusPublished - Aug 2005

Scopus Subject Areas

  • Pharmacology
  • Drug Discovery

User-Defined Keywords

  • Actinomycete
  • Antimicrobial activity
  • Antimycin
  • Fungicide
  • Macrodiolide
  • Streptomyces sp.


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