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A Metal-Based Inhibitor of NEDD8-Activating Enzyme
Hai Jing Zhong
, Hui Yang
, Daniel Shiu Hin Chan
, Chung Hang Leung
, Hui Min Wang
, Dik Lung Ma
*
*
Corresponding author for this work
Department of Chemistry
Research output
:
Contribution to journal
›
Journal article
›
peer-review
46
Citations (Scopus)
Overview
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Dive into the research topics of 'A Metal-Based Inhibitor of NEDD8-Activating Enzyme'. Together they form a unique fingerprint.
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Chemistry
Rhodium
100%
Enzyme Activity
100%
Molecular Model
100%
Phenylpyridine
100%
Enzyme Inhibitor
100%
Heterodimer
100%
Dipyridophenazine
100%
Phenazine
100%
Keyphrases
Metal-based Inhibitors
100%
NEDD8-activating Enzyme
100%
Dppz
40%
MLN4924
40%
Binding Pocket
20%
Metal Complexes
20%
Binding Mode
20%
Cancer Cells
20%
Cell-based
20%
NF-B
20%
Enzyme Activity
20%
2-Phenylpyridine
20%
Rhodium(III) Complex
20%
Substrate Degradation
20%
Cyclometallated
20%
Cell-free
20%
Phenazine
20%
Molecular Modelling Analysis
20%
NEDDylation Pathway
20%
UBA3
20%
Dipyridophenazine
20%
Pharmacology, Toxicology and Pharmaceutical Science
Pevonedistat
100%
Malignant Neoplasm
50%
Reduced Nicotinamide Adenine Dinucleotide Dehydrogenase (Ubiquinone)
50%
Metal Complex
50%
Enzyme Inhibitor
50%
Heterodimer
50%
Phenazine
50%
Biochemistry, Genetics and Molecular Biology
Enzyme
100%
NEDD8
100%
Cancer Cell
20%
Enzyme Activity
20%
Molecular Model
20%
Neddylation
20%
Enzyme Inhibitor
20%