@article{1698236a03ae4af1bcf96104ebcd9239,
title = "A luminescence switch-on assay for the detection of specific gene deletion using G-quadruplex DNA and silver nanoclusters",
abstract = "A switch-on gene deletion detection platform is reported based on the alteration of the effective distance between G-quadruplex DNA and silver nanoclusters (AgNCs). Moreover, the role of the G-quadruplex structure in interacting with AgNCs has also been demonstrated. The detection of the deletion mutants of LMP1 and CCR5 genes is performed as the proof-of-concept of our assay. Finally, the potential biological application of the assay was demonstrated in 10% v/v human serum.",
author = "Modi Wang and Wanhe Wang and Chenfu LIU and Jinbiao Liu and Kang, {Tian Shu} and Leung, {Chung Hang} and MA, {Edmond Dik Lung}",
note = "Funding Information: This work was supported by Hong Kong Baptist University (FRG2/14-15/004 and FRG2/15-16/002), the Health and Medical Research Fund (HMRF/14130522), the Research Grants Council (HKBU/201811, HKBU/204612 and HKBU/201913), the French Agence Nationale de la Recherche/Research Grants Council Joint Research Scheme (AHKBU201/12; Oligoswitch ANR-12-IS07-0001), National Natural Science Foundation of China (21575121), Guangdong Province Natural Science Foundation (2015A030313816), Hong Kong Baptist University Century Club Sponsorship Scheme 2015, Interdisciplinary Research Matching Scheme (RC-IRMS/14-15/06), the Science and Technology Development Fund, Macao SAR (098/2014/A2), the University of Macau (MYRG091(Y3-L2)-ICMS12-LCH and MYRG2015-00137-ICMS-QRCM).",
year = "2017",
month = jan,
doi = "10.1039/c6qm00068a",
language = "English",
volume = "1",
pages = "128--131",
journal = "Materials Chemistry Frontiers",
issn = "2052-1537",
publisher = "Royal Society of Chemistry",
number = "1",
}