@article{804b5cdd0ddf4c87ba893625fa57ab17,
title = "A long-lived iridium(iii) chemosensor for the real-time detection of GHB",
abstract = "Gamma-hydroxybutyric acid (GHB) is a commonly used “date rape” drug in drug-facilitated sexual assaults (DFSA) due to its low price and ready availability, and it is more quickly excreted from the human body than other drugs. Therefore, the development of a real-time detection method for GHB could help facilitate law enforcement agencies in tackling DFSA. In this work, a long-lived iridium(iii) chemosensor 1 has been synthesized for the switch-off detection of GHB. Upon addition of GHB to an aqueous solution of the iridium(iii) complex 1, a significant luminescence quenching occurred that could be observed by the naked eye under UV illumination. The luminescence signal of the iridium(iii) complex 1 could also be distinguished from strongly fluorescent media using time-resolved emission spectroscopy.",
author = "Wanhe Wang and Dong, {Zhen Zhen} and Guanjun Yang and Leung, {Chung Hang} and Sheng Lin and Ma, {Dik Lung}",
note = "Funding Information: This work is supported by Hong Kong Baptist University (FRG2/ 15-16/002), the Health and Medical Research Fund (HMRF/ 14130522), the Research Grants Council (HKBU/12301115, HKBU/204612 and HKBU/201913), the French Agence Nationale de la Recherche/Research Grants Council Joint Research Scheme (AHKBU201/12; Oligoswitch ANR-12-IS07-0001), the National Natural Science Foundation of China (21575121 and 21628502), the Guangdong Province Natural Science Foundation (2015A030313816), the Hong Kong Baptist University Century Club Sponsorship Scheme 2016, the Interdisciplinary Research Matching Scheme (RC-IRMS/15-16/03), the Science and Technology Development Fund,Macao SAR (007/2014/AMJ and 077/2016/A2), the University of Macau (MYRG2015-00137-ICMS-QRCM, MYRG2016-00151-ICMSQRCM and MRG044/LCH/2015/ICMS).",
year = "2017",
doi = "10.1039/C6TB03396B",
language = "English",
volume = "5",
pages = "2739--2742",
journal = "Journal of Materials Chemistry B",
issn = "2050-750X",
publisher = "Royal Society of Chemistry",
number = "15",
}