A long-lived iridium(iii) chemosensor for the real-time detection of GHB

Wanhe Wang, Zhen Zhen Dong, Guanjun Yang, Chung Hang Leung, Sheng Lin*, Edmond Dik Lung MA

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

20 Citations (Scopus)


Gamma-hydroxybutyric acid (GHB) is a commonly used “date rape” drug in drug-facilitated sexual assaults (DFSA) due to its low price and ready availability, and it is more quickly excreted from the human body than other drugs. Therefore, the development of a real-time detection method for GHB could help facilitate law enforcement agencies in tackling DFSA. In this work, a long-lived iridium(iii) chemosensor 1 has been synthesized for the switch-off detection of GHB. Upon addition of GHB to an aqueous solution of the iridium(iii) complex 1, a significant luminescence quenching occurred that could be observed by the naked eye under UV illumination. The luminescence signal of the iridium(iii) complex 1 could also be distinguished from strongly fluorescent media using time-resolved emission spectroscopy.

Original languageEnglish
Pages (from-to)2739-2742
Number of pages4
JournalJournal of Materials Chemistry B
Issue number15
Publication statusPublished - 2017

Scopus Subject Areas

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)


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