A long lifetime iridium(III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish

Jin Biao Liu; Chao Yang; Chung Nga Ko; Kasipandi Vellaisamy; Binrui Yang; Ming Yuen Lee; Chung Hang Leung; Edmond Dik Lung Ma

doi:10.1016/j.snb.2016.12.083

A long lifetime iridium(III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish

Jin Biao Liu^*, Chao Yang, Chung Nga Ko, Kasipandi Vellaisamy, Binrui Yang, Ming Yuen Lee, Chung Hang Leung, Edmond Dik Lung Ma

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

86 Citations (Scopus)

Abstract

A long-lived iridium(III) complex probe Ir_1 for bisulfite detection has been synthesized. The iridium(III) complex probe Ir_1, containing double aldehyde groups in the N^N donor ligand, can react with bisulfite to form an adduct with enhanced luminescence. The interaction of probe Ir_1 with bisulfite was investigated through NMR and emission titration experiments. Upon the addition of bisulfite, probe Ir_1 displayed more than a 4-fold luminescence enhancement, and a detection limit of 0.35 μM was recorded. Probe Ir_1 shows a large Stokes shift (280 nm) and a long-lived luminescence which allows it to be distinguished from autofluorescent media through time-resolved emission spectroscopy (TRES). Finally, the applications of probe Ir_1 to the detection of bisulfite in living cells and zebrafish were described.

Original language	English
Pages (from-to)	971-976
Number of pages	6
Journal	Sensors and Actuators, B: Chemical
Volume	243
DOIs	https://doi.org/10.1016/j.snb.2016.12.083
Publication status	Published - May 2017

Scopus Subject Areas

Electronic, Optical and Magnetic Materials
Instrumentation
Condensed Matter Physics
Surfaces, Coatings and Films
Metals and Alloys
Electrical and Electronic Engineering
Materials Chemistry

User-Defined Keywords

Bisulfite
Iridium(III) complex
Luminescence
Probe

Access to Document

10.1016/j.snb.2016.12.083

Cite this

@article{e62d5f7a76374487b914fce6c3b8e6a6,

title = "A long lifetime iridium(III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish",

abstract = "A long-lived iridium(III) complex probe Ir_1 for bisulfite detection has been synthesized. The iridium(III) complex probe Ir_1, containing double aldehyde groups in the N^N donor ligand, can react with bisulfite to form an adduct with enhanced luminescence. The interaction of probe Ir_1 with bisulfite was investigated through NMR and emission titration experiments. Upon the addition of bisulfite, probe Ir_1 displayed more than a 4-fold luminescence enhancement, and a detection limit of 0.35 μM was recorded. Probe Ir_1 shows a large Stokes shift (280 nm) and a long-lived luminescence which allows it to be distinguished from autofluorescent media through time-resolved emission spectroscopy (TRES). Finally, the applications of probe Ir_1 to the detection of bisulfite in living cells and zebrafish were described.",

keywords = "Bisulfite, Iridium(III) complex, Luminescence, Probe",

author = "Liu, {Jin Biao} and Chao Yang and Ko, {Chung Nga} and Kasipandi Vellaisamy and Binrui Yang and Lee, {Ming Yuen} and Leung, {Chung Hang} and Ma, {Edmond Dik Lung}",

year = "2017",

month = may,

doi = "10.1016/j.snb.2016.12.083",

language = "English",

volume = "243",

pages = "971--976",

journal = "Sensors and Actuators, B: Chemical",

issn = "0925-4005",

publisher = "Elsevier",

}

TY - JOUR

T1 - A long lifetime iridium(III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish

AU - Liu, Jin Biao

AU - Yang, Chao

AU - Ko, Chung Nga

AU - Vellaisamy, Kasipandi

AU - Yang, Binrui

AU - Lee, Ming Yuen

AU - Leung, Chung Hang

AU - Ma, Edmond Dik Lung

PY - 2017/5

Y1 - 2017/5

N2 - A long-lived iridium(III) complex probe Ir_1 for bisulfite detection has been synthesized. The iridium(III) complex probe Ir_1, containing double aldehyde groups in the N^N donor ligand, can react with bisulfite to form an adduct with enhanced luminescence. The interaction of probe Ir_1 with bisulfite was investigated through NMR and emission titration experiments. Upon the addition of bisulfite, probe Ir_1 displayed more than a 4-fold luminescence enhancement, and a detection limit of 0.35 μM was recorded. Probe Ir_1 shows a large Stokes shift (280 nm) and a long-lived luminescence which allows it to be distinguished from autofluorescent media through time-resolved emission spectroscopy (TRES). Finally, the applications of probe Ir_1 to the detection of bisulfite in living cells and zebrafish were described.

AB - A long-lived iridium(III) complex probe Ir_1 for bisulfite detection has been synthesized. The iridium(III) complex probe Ir_1, containing double aldehyde groups in the N^N donor ligand, can react with bisulfite to form an adduct with enhanced luminescence. The interaction of probe Ir_1 with bisulfite was investigated through NMR and emission titration experiments. Upon the addition of bisulfite, probe Ir_1 displayed more than a 4-fold luminescence enhancement, and a detection limit of 0.35 μM was recorded. Probe Ir_1 shows a large Stokes shift (280 nm) and a long-lived luminescence which allows it to be distinguished from autofluorescent media through time-resolved emission spectroscopy (TRES). Finally, the applications of probe Ir_1 to the detection of bisulfite in living cells and zebrafish were described.

KW - Bisulfite

KW - Iridium(III) complex

KW - Luminescence

KW - Probe

UR - http://www.scopus.com/inward/record.url?scp=85006868127&partnerID=8YFLogxK

U2 - 10.1016/j.snb.2016.12.083

DO - 10.1016/j.snb.2016.12.083

M3 - Journal article

AN - SCOPUS:85006868127

SN - 0925-4005

VL - 243

SP - 971

EP - 976

JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

ER -

A long lifetime iridium(III) complex as a sensitive luminescent probe for bisulfite detection in living zebrafish

Abstract

Scopus Subject Areas

User-Defined Keywords

Access to Document

Other files and links

Fingerprint

Cite this