@article{29baf1affe6e4b90a854f5c2c19ce318,
title = "A labile iridium(III) complex-based luminogenic probe for the ratiometric detection of dithiocarbamate compounds in living system",
abstract = "Dithiocarbamate bioactive compounds are extensively used in agriculture and medicine, but traditional methods for the detection of dithiocarbamates are limited by complicated sensing systems and incompatibility with living systems. In this work, we developed an iridium(III) solvento complex (1) for the luminogenic detection of dithiocarbamates. The probe can sensitively detect a range of dithiocarbamates including sodium diethyldithiocarbamate (NDDC), sodium dimethyldithiocarbamate (SDDC) and ammonium pyrrolidinedithiocarbamate (APDC) in aqueous buffer with up to 10.3-fold luminescence enhancement and limits of detection in the submicromolar range. Moreover, the probe has the capacity to detect dithiocarbamates in water and drink samples as well as in the presence of living cells. Importantly, this probe is robust to potential interferent including other coordinative thiols and histidine. This work serves as a good starting point for developing a single molecule-based sensing system for dithiocarbamates, and opens the door for developing new imaging probe for dithiocarbamates.",
keywords = "Cell imaging, Dithiocarbamates, Iridium(III) solvento complex, Luminogenic detection, Real samples",
author = "Chuankai Lin and Xueliang Wang and Nao, {Sang Cuo} and Jing Wang and Jinbiao Liu and Ma, {Dik Lung} and Zhu, {Wei Guo} and Leung, {Chung Hang} and Wanhe Wang",
note = "This work is supported by the Natural Science Basic Research Program of Shaanxi ( 2021JQ-089 , 2021JQ-092 ), the National Natural Science Foundation of China ( 21961014 , 22101230 ), the Fundamental Research Funds for the Central Universities ( 31020200QD017 , 31020200QD023 ), Shanghai Sailing Program ( 21YF1451200 ), the Natural Science Foundation of Chongqing , China ( cstc2021jcyj-msxmX0659 ), the Guangdong Basic and Applied Basic Research Foundation ( 2021A1515110840 ), the Natural Science Foundation of Jiangxi Province , China ( 20192BCBL23009 ), the Youth Jinggang Scholars Program in Jiangxi Province, Postdoctoral Merit Program of Jiangxi Province ( 2021KY21 ), the Science and Technology Development Fund (Macau SAR, China) ( 0007/2020/A1 , 0020/2022/A1 ), the State Key Laboratory of Quality Research in Chinese Medicine (University of Macau) ( SKL-QRCM(UM)-2020-2022 ), the University of Macau (University of Macau) ( MYRG2019-00002-ICMS , MYRG2020–00017-ICMS ), 2022 Internal Research Grant of SKL-QRCM (University of Macau) ( QRCM-IRG2022-011 ). Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",
year = "2023",
month = mar,
day = "1",
doi = "10.1016/j.snb.2022.133133",
language = "English",
volume = "378",
journal = "Sensors and Actuators B: Chemical",
issn = "0925-4005",
publisher = "Elsevier B.V.",
}