Abstract
We report herein the use of an exonuclease III and G-quadruplex probe to construct a G-quadruplex-based luminescence detection platform for Hg2+. Unlike common DNA-based Hg2+ detection methods, when using the dsDNA probe to monitor the hairpin formation, the intercalation of the dsDNA probe may be influenced by the distortion of dsDNA. This 'mix-and-detect' methodology utilized the G-quadruplex probe as the signal transducer and is simple, rapid, convenient to use and can detect down to 20 nM of Hg2+.
Original language | English |
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Article number | 065004 |
Journal | Science and Technology of Advanced Materials |
Volume | 16 |
Issue number | 6 |
DOIs | |
Publication status | Published - 17 Nov 2015 |
Scopus Subject Areas
- Materials Science(all)
User-Defined Keywords
- exonuclease III
- G-quadruplex
- iridium(III)
- mercury(II) ion