@article{1f22f23d835c48c488de08a95548a7ad,
title = "A highly selective g-quadruplex-based luminescent switch-on probe for the detection of gene deletion",
abstract = "A G-quadruplex-based switch-on luminescence assay has been developed for the detection of gene deletion using a cyclometallated iridium(III) complex as a G-quadruplex-selective probe. Upon hybridization with the target DNA, the two split G-quadruplex-forming sequences assemble into a split G-quadruplex, which greatly enhances the luminescence emission of the iridium(III) probe. The assay is simple and highly selective.",
author = "He, {Hong Zhang} and Chan, {Daniel Shiu Hin} and Leung, {Chung Hang} and Ma, {Dik Lung}",
note = "This work is supported by Hong Kong Baptist University (FRG2/10-11/008 and FRG2/11-12/009), Environment and Conservation Fund (ECF Project 3/2010), Centre for Cancer and Inflammation Research, School of Chinese Medicine (CCIR-SCM, HKBU), the Research Fund for the Control of Infectious Diseases (RFCID/11101212), the Research Grants Council (HKBU/201811), the University of Macau (Start-up Research Grant to C.-H. Leung), MYRG091(Y1-L2)-ICMS12-LCH and MYRG121(Y1-L3)-ICMS12-LCH).",
year = "2012",
month = aug,
day = "28",
doi = "10.1039/c2cc32253f",
language = "English",
volume = "48",
pages = "9462--9464",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "76",
}