A Highly Convergent Cascade Cyclization to cis-Hydrindanes with All-Carbon Quaternary Centers and Its Application in the Synthesis of the Aglycon of Dendronobiloside A

Yejian Han, Lizhi Zhu, Yuan Gao, Chi Sing Lee*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

28 Citations (Scopus)

Abstract

An efficient and versatile ZnBr2-catalyzed Diels-Alder/ carbocyclization cascade reaction has been developed for construction of highly functionalized cis-hydrindanes (70-96% yields with high diastereoselectivity), and it has been successfully utilized in the synthesis of the aglycon of dendronobiloside A.

Original languageEnglish
Pages (from-to)588-591
Number of pages4
JournalOrganic Letters
Volume13
Issue number4
Early online date10 Jan 2011
DOIs
Publication statusPublished - 18 Feb 2011

Fingerprint

Dive into the research topics of 'A Highly Convergent Cascade Cyclization to cis-Hydrindanes with All-Carbon Quaternary Centers and Its Application in the Synthesis of the Aglycon of Dendronobiloside A'. Together they form a unique fingerprint.

Cite this