@article{efd5ab6491f94f2081427bf38e1fbd42,
title = "A G-triplex luminescent switch-on probe for the detection of mung bean nuclease activity",
abstract = "A cyclometallated Ir(III) complex was synthesised and evaluated for the ability to act as a luminescent G-triplex probe. The iridium(III) complex 1 [Ir(phq)2(2,9-dmphen)]PF6 (where phq = 2-phenylquinoline; 2,9-dmphen = 2,9-dimethyl-1,10-phenanthroline) exhibited high luminescence for G-triplex DNA over dsDNA and ssDNA, and was employed to construct a label-free G-triplex-based assay for mung bean nuclease activity in aqueous solution. This method was highly sensitive and selective for MB nuclease activity over other DNA-modifying enzymes.",
author = "Ma, {Edmond Dik Lung} and Lihua Lu and Sheng Lin and Bingyong He and Leung, {Chung Hang}",
note = "Funding information: This work is supported by Hong Kong Baptist University (FRG2/13-14/008), the Centre for Cancer and Inflammation Research, School of Chinese Medicine (CCIR-SCM, HKBU), the Health and Medical Research Fund (HMRF/13121482), the Research Grants Council (HKBU/201811, HKBU/204612 and HKBU/201913), the French National Research Agency/Research Grants Council Joint Research Scheme (A-HKBU201/12), the State Key Laboratory of Synthetic Chemistry, the Science and Technology Development Fund, Macao SAR (103/2012/A3) and the University of Macau (MYRG091(Y3-L2)-ICMS12-LCH, MYRG121(Y3-L2)-ICMS12-LCH and MRG023/LCH/2013/ICMS). Publisher ocpyright: {\textcopyright} The Royal Society of Chemistry 2015",
year = "2015",
month = jan,
day = "21",
doi = "10.1039/c4tb01569j",
language = "English",
volume = "3",
pages = "348--352",
journal = "Journal of Materials Chemistry B",
issn = "2050-750X",
publisher = "Royal Society of Chemistry",
number = "3",
}