A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase

Ka Ho Leung; Hong Zhang He; Victor Pui Yan Ma; Hui Yang; Daniel Shiu Hin Chan; Chung Hang Leung; Dik Lung Ma

doi:10.1039/c2ra21996d

A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase

Ka Ho Leung, Hong Zhang He, Victor Pui Yan Ma, Hui Yang, Daniel Shiu Hin Chan, Chung Hang Leung^*, Dik Lung Ma

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

32 Citations (Scopus)

Abstract

A novel G-quadruplex-selective luminescent iridium(iii) complex has been employed as a signal-transducing element for the sensitive and selective switch-on detection of sub-nanomolar human neutrophil elastase (HNE) in homogenous solution.

Original language	English
Pages (from-to)	1656-1659
Number of pages	4
Journal	RSC Advances
Volume	3
Issue number	6
DOIs	https://doi.org/10.1039/c2ra21996d
Publication status	Published - 14 Feb 2013

Scopus Subject Areas

Chemistry(all)
Chemical Engineering(all)

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10.1039/c2ra21996d

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title = "A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase",

abstract = "A novel G-quadruplex-selective luminescent iridium(iii) complex has been employed as a signal-transducing element for the sensitive and selective switch-on detection of sub-nanomolar human neutrophil elastase (HNE) in homogenous solution.",

author = "Leung, {Ka Ho} and He, {Hong Zhang} and Ma, {Victor Pui Yan} and Hui Yang and Chan, {Daniel Shiu Hin} and Leung, {Chung Hang} and Ma, {Dik Lung}",

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AU - Leung, Ka Ho

AU - He, Hong Zhang

AU - Ma, Victor Pui Yan

AU - Yang, Hui

AU - Chan, Daniel Shiu Hin

AU - Leung, Chung Hang

AU - Ma, Dik Lung

PY - 2013/2/14

Y1 - 2013/2/14

N2 - A novel G-quadruplex-selective luminescent iridium(iii) complex has been employed as a signal-transducing element for the sensitive and selective switch-on detection of sub-nanomolar human neutrophil elastase (HNE) in homogenous solution.

AB - A novel G-quadruplex-selective luminescent iridium(iii) complex has been employed as a signal-transducing element for the sensitive and selective switch-on detection of sub-nanomolar human neutrophil elastase (HNE) in homogenous solution.

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U2 - 10.1039/c2ra21996d

DO - 10.1039/c2ra21996d

M3 - Journal article

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JO - RSC Advances

JF - RSC Advances

IS - 6

ER -

A G-quadruplex-selective luminescent switch-on probe for the detection of sub-nanomolar human neutrophil elastase

Abstract

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