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A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag+ions based on the exonuclease III-mediated digestion of C-Ag+-C DNA

  • Modi Wang
  • , Ka Ho Leung
  • , Sheng Lin
  • , Daniel Shiu Hin Chan
  • , Chung Hang Leung
  • , Dik Lung Ma*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

24 Citations (Scopus)

Abstract

We report herein the ability of exonuclease III to cleave C-Ag+-C mismatched DNA, which was utilised for the construction of an exonuclease III-assisted, label-free, switch-on luminescent platform for Ag+ions using a novel G-quadruplex-selective iridium(iii) complex.

Original languageEnglish
Pages (from-to)6467-6471
Number of pages5
JournalJournal of Materials Chemistry B
Volume20
Issue number38
DOIs
Publication statusPublished - 2014

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