A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag+ions based on the exonuclease III-mediated digestion of C-Ag+-C DNA

Modi Wang, Ka Ho Leung, Sheng Lin, Daniel Shiu Hin Chan, Chung Hang Leung, Dik Lung Ma*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

24 Citations (Scopus)

Abstract

We report herein the ability of exonuclease III to cleave C-Ag+-C mismatched DNA, which was utilised for the construction of an exonuclease III-assisted, label-free, switch-on luminescent platform for Ag+ions using a novel G-quadruplex-selective iridium(iii) complex.

Original languageEnglish
Pages (from-to)6467-6471
Number of pages5
JournalJournal of Materials Chemistry B
Volume20
Issue number38
DOIs
Publication statusPublished - 2014

Scopus Subject Areas

  • General Chemistry
  • Biomedical Engineering
  • General Materials Science

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