A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag+ions based on the exonuclease III-mediated digestion of C-Ag+-C DNA

Modi Wang; Ka Ho Leung; Sheng Lin; Daniel Shiu Hin Chan; Chung Hang Leung; Edmond Dik Lung MA

doi:10.1039/c4tb01140f

A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag⁺ions based on the exonuclease III-mediated digestion of C-Ag⁺-C DNA

Modi Wang, Ka Ho Leung, Sheng Lin, Daniel Shiu Hin Chan, Chung Hang Leung, Edmond Dik Lung MA^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

We report herein the ability of exonuclease III to cleave C-Ag⁺-C mismatched DNA, which was utilised for the construction of an exonuclease III-assisted, label-free, switch-on luminescent platform for Ag⁺ions using a novel G-quadruplex-selective iridium(iii) complex. This journal is

Original language	English
Pages (from-to)	6467-6471
Number of pages	5
Journal	Journal of Materials Chemistry B
Volume	20
Issue number	38
DOIs	https://doi.org/10.1039/c4tb01140f
Publication status	Published - 2014

Scopus Subject Areas

Chemistry(all)
Biomedical Engineering
Materials Science(all)

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10.1039/c4tb01140f

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abstract = "We report herein the ability of exonuclease III to cleave C-Ag+-C mismatched DNA, which was utilised for the construction of an exonuclease III-assisted, label-free, switch-on luminescent platform for Ag+ions using a novel G-quadruplex-selective iridium(iii) complex. This journal is",

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AU - Leung, Ka Ho

AU - Lin, Sheng

AU - Chan, Daniel Shiu Hin

AU - Leung, Chung Hang

AU - MA, Edmond Dik Lung

PY - 2014

Y1 - 2014

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AB - We report herein the ability of exonuclease III to cleave C-Ag+-C mismatched DNA, which was utilised for the construction of an exonuclease III-assisted, label-free, switch-on luminescent platform for Ag+ions using a novel G-quadruplex-selective iridium(iii) complex. This journal is

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VL - 20

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EP - 6471

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A G-quadruplex-based, label-free, switch-on luminescent detection assay for Ag⁺ions based on the exonuclease III-mediated digestion of C-Ag⁺-C DNA

Abstract

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