A novel FRET fluorescent sensor SPAQ containing 8-aminoquinoline (donor) and spiropyran derivative (acceptor) was designed and synthesized for detecting Zn2+. The probe successfully exhibited a fluorescence turn on and ratiometric response for Zn2+ in ethanol solution with high selectivity. Upon excitation at 370 nm, the modulation of the emission intensity of SPAQ at 645 and 470 nm was achieved in the presence of Zn2+ by fluorescent resonance energy transfer (FRET) and chelation-enhanced fluorescence (CHEF) effects.
|Number of pages||5|
|Publication status||Published - 7 Jul 2010|
Scopus Subject Areas
- Drug Discovery
- Organic Chemistry