A FRET fluorescent chemosensor SPAQ for Zn2+ based on a dyad bearing spiropyran and 8-aminoquinoline unit

Jian Fa Zhu; Han Yuan; Wing Hong Chan; Albert W.M. Lee

doi:10.1016/j.tetlet.2010.04.127

A FRET fluorescent chemosensor SPAQ for Zn²⁺ based on a dyad bearing spiropyran and 8-aminoquinoline unit

Jian Fa Zhu, Han Yuan, Wing Hong Chan^*, Albert W.M. Lee

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

50 Citations (Scopus)

Abstract

A novel FRET fluorescent sensor SPAQ containing 8-aminoquinoline (donor) and spiropyran derivative (acceptor) was designed and synthesized for detecting Zn²⁺. The probe successfully exhibited a fluorescence turn on and ratiometric response for Zn²⁺ in ethanol solution with high selectivity. Upon excitation at 370 nm, the modulation of the emission intensity of SPAQ at 645 and 470 nm was achieved in the presence of Zn²⁺ by fluorescent resonance energy transfer (FRET) and chelation-enhanced fluorescence (CHEF) effects.

Original language	English
Pages (from-to)	3550-3554
Number of pages	5
Journal	Tetrahedron Letters
Volume	51
Issue number	27
DOIs	https://doi.org/10.1016/j.tetlet.2010.04.127
Publication status	Published - 7 Jul 2010

Scopus Subject Areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2010.04.127

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title = "A FRET fluorescent chemosensor SPAQ for Zn2+ based on a dyad bearing spiropyran and 8-aminoquinoline unit",

abstract = "A novel FRET fluorescent sensor SPAQ containing 8-aminoquinoline (donor) and spiropyran derivative (acceptor) was designed and synthesized for detecting Zn2+. The probe successfully exhibited a fluorescence turn on and ratiometric response for Zn2+ in ethanol solution with high selectivity. Upon excitation at 370 nm, the modulation of the emission intensity of SPAQ at 645 and 470 nm was achieved in the presence of Zn2+ by fluorescent resonance energy transfer (FRET) and chelation-enhanced fluorescence (CHEF) effects.",

author = "Zhu, {Jian Fa} and Han Yuan and Chan, {Wing Hong} and Lee, {Albert W.M.}",

note = "Funding Information: The work was supported by a grant from the Research Grant Council of Hong Kong ( HKBU 200407 ). ",

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T1 - A FRET fluorescent chemosensor SPAQ for Zn2+ based on a dyad bearing spiropyran and 8-aminoquinoline unit

AU - Zhu, Jian Fa

AU - Yuan, Han

AU - Chan, Wing Hong

AU - Lee, Albert W.M.

N1 - Funding Information: The work was supported by a grant from the Research Grant Council of Hong Kong ( HKBU 200407 ).

PY - 2010/7/7

Y1 - 2010/7/7

N2 - A novel FRET fluorescent sensor SPAQ containing 8-aminoquinoline (donor) and spiropyran derivative (acceptor) was designed and synthesized for detecting Zn2+. The probe successfully exhibited a fluorescence turn on and ratiometric response for Zn2+ in ethanol solution with high selectivity. Upon excitation at 370 nm, the modulation of the emission intensity of SPAQ at 645 and 470 nm was achieved in the presence of Zn2+ by fluorescent resonance energy transfer (FRET) and chelation-enhanced fluorescence (CHEF) effects.

AB - A novel FRET fluorescent sensor SPAQ containing 8-aminoquinoline (donor) and spiropyran derivative (acceptor) was designed and synthesized for detecting Zn2+. The probe successfully exhibited a fluorescence turn on and ratiometric response for Zn2+ in ethanol solution with high selectivity. Upon excitation at 370 nm, the modulation of the emission intensity of SPAQ at 645 and 470 nm was achieved in the presence of Zn2+ by fluorescent resonance energy transfer (FRET) and chelation-enhanced fluorescence (CHEF) effects.

UR - http://www.scopus.com/inward/record.url?scp=77954244904&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2010.04.127

DO - 10.1016/j.tetlet.2010.04.127

M3 - Journal article

AN - SCOPUS:77954244904

SN - 0040-4039

VL - 51

SP - 3550

EP - 3554

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 27

ER -

A FRET fluorescent chemosensor SPAQ for Zn²⁺ based on a dyad bearing spiropyran and 8-aminoquinoline unit

Abstract

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