A facile total synthesis of isoquinolone alkaloids

Albert W M LEE*, Wing Hong CHAN, Eddy T.T. Chan

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

27 Citations (Scopus)


Four isoquinolone alkaloids, N-methylcorydaldine 8a, oxyhydrastinine 8b, 6,7-dimethoxy-2-methylisocarbostyril 9a and doryanine 9b, have been efficiently synthesized from phenyl vinyl sulfoxide via the Pummerer type rearrangement as a key step.

Original languageEnglish
Pages (from-to)309-310
Number of pages2
JournalJournal of the Chemical Society, Perkin Transactions 1
Issue number3
Publication statusPublished - 1992

Scopus Subject Areas

  • Chemistry(all)


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