@article{498fae3211f24d9fa0e2c156151d5e4d,
title = "A dual-functional molecular strategy for in situ suppressing and visualizing of neuraminidase in aqueous solution using iridium(III) complexes",
abstract = "We have designed for the first time a dual-functional luminescent probe and inhibitor of neuraminidase (NA), a key influenza target. The lead iridium(iii) complex exhibited enhanced inhibition against NA compared to the FDA-approved antiviral drug, oseltamivir, and could detect NA even in the presence of an autofluorescent background.",
author = "Chun Wu and Wu, {Ke Jia} and Liu, {Jin Biao} and Zhou, {Xiao Ming} and Leung, {Chung Hang} and MA, {Edmond Dik Lung}",
note = "Funding Information: This work is supported by Hong Kong Baptist University (FRG2/17-18/003), the Health and Medical Research Fund (HMRF/14150561), the National Natural Science Foundation of China (21575121, 21775131 and 21762018), the Hong Kong Baptist University Century Club Sponsorship Scheme 2018, the Interdisciplinary Research Matching Scheme (RC-IRMS/16-17/03), Interdisciplinary Research Clusters Matching Scheme (RC-IRCs/ 17-18/03), Collaborative Research Fund (C5026-16G), SKLEBA and HKBU Strategic Development Fund (SKLP_1718_P04), the Science and Technology Development Fund, Macao SAR (0072/2018/A2), and the University of Macau (MYRG2016-00151-ICMS-QRCM and MYRG2018-00187-ICMS).",
year = "2019",
month = jun,
day = "7",
doi = "10.1039/c9cc02189b",
language = "English",
volume = "55",
pages = "6353--6356",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "45",
}
