A DLM/FD/IB method for simulating compound vesicle motion under creeping flow condition

Tsorng Whay Pan*, Shihai Zhao, Xiting Niu, Roland GLOWINSKI

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

6 Citations (Scopus)


In this article we present first a new distributed Lagrange multiplier/fictitious domain (DLM/FD) method for simulating fluid-particle interaction in Stokes flow. A conjugate gradient method driven by both pressure and distributed Lagrange multiplier, called one-shot method, has been developed to solve the discrete Stokes problem while enforcing the rigid body motion within the region occupied by the particle. The methodology is validated by comparing the numerical results of a neutrally buoyant particle of either a circular or elliptic shape with the associated Jeffery's solutions. We have successively combined the above methodology with an immersed boundary (IB) method and an elastic membrane modeled by a spring network to simulate the dynamics of a compound vesicle. In simple shear flow under creeping flow condition, the results are consistent with those obtained in literature. In Poiseuille flow, the compound vesicle motion is dominated by the motion of the vesicle membrane as expected and stays in the central region of the channel.

Original languageEnglish
Pages (from-to)241-253
Number of pages13
JournalJournal of Computational Physics
Publication statusPublished - 1 Nov 2015

Scopus Subject Areas

  • Numerical Analysis
  • Modelling and Simulation
  • Physics and Astronomy (miscellaneous)
  • Physics and Astronomy(all)
  • Computer Science Applications
  • Computational Mathematics
  • Applied Mathematics

User-Defined Keywords

  • Compound vesicle
  • Distributed Lagrange multiplier/fictitious domain method
  • Immersed boundary method
  • Neutrally buoyant particle
  • Stokes flow


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