A coumarin-based fluorescent probe for recognition of Cu2+ and fast detection of histidine in hard-to-transfect cells by a sensing ensemble approach

Qi-Hua You; Albert Wai-Ming Lee; Wing-Hong Chan; Xiao-Ming Zhu; Ken Cham-Fai Leung

doi:10.1039/c4cc00521j

A coumarin-based fluorescent probe for recognition of Cu²⁺ and fast detection of histidine in hard-to-transfect cells by a sensing ensemble approach

Qi-Hua You, Albert Wai-Ming Lee, Wing-Hong Chan^*, Xiao-Ming Zhu, Ken Cham-Fai Leung

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

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Abstract

A coumarin-based fluorescent chemosensor CAQA has been synthesized. It can selectively and sensitively recognize Cu²⁺in aqueous acetonitrile solutions. Using the Cu-containing complex CAQA-Cu²⁺as a sensing ensemble, the device demonstrates highly selective recognition of His/biothiols and was applied in fluorescence imaging of histidine in hard-to-transfect living cells.

Original language	English
Pages (from-to)	6207-6210
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	47
Early online date	3 Mar 2014
DOIs	https://doi.org/10.1039/c4cc00521j
Publication status	Published - Jun 2014

Scopus Subject Areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "A coumarin-based fluorescent probe for recognition of Cu2+ and fast detection of histidine in hard-to-transfect cells by a sensing ensemble approach",

abstract = "A coumarin-based fluorescent chemosensor CAQA has been synthesized. It can selectively and sensitively recognize Cu2+in aqueous acetonitrile solutions. Using the Cu-containing complex CAQA-Cu2+as a sensing ensemble, the device demonstrates highly selective recognition of His/biothiols and was applied in fluorescence imaging of histidine in hard-to-transfect living cells.",

author = "Qi-Hua You and Lee, {Albert Wai-Ming} and Wing-Hong Chan and Xiao-Ming Zhu and Leung, {Ken Cham-Fai}",

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T1 - A coumarin-based fluorescent probe for recognition of Cu2+ and fast detection of histidine in hard-to-transfect cells by a sensing ensemble approach

AU - You, Qi-Hua

AU - Lee, Albert Wai-Ming

AU - Chan, Wing-Hong

AU - Zhu, Xiao-Ming

AU - Leung, Ken Cham-Fai

PY - 2014/6

Y1 - 2014/6

N2 - A coumarin-based fluorescent chemosensor CAQA has been synthesized. It can selectively and sensitively recognize Cu2+in aqueous acetonitrile solutions. Using the Cu-containing complex CAQA-Cu2+as a sensing ensemble, the device demonstrates highly selective recognition of His/biothiols and was applied in fluorescence imaging of histidine in hard-to-transfect living cells.

AB - A coumarin-based fluorescent chemosensor CAQA has been synthesized. It can selectively and sensitively recognize Cu2+in aqueous acetonitrile solutions. Using the Cu-containing complex CAQA-Cu2+as a sensing ensemble, the device demonstrates highly selective recognition of His/biothiols and was applied in fluorescence imaging of histidine in hard-to-transfect living cells.

UR - http://www.scopus.com/inward/record.url?scp=84901036335&partnerID=8YFLogxK

U2 - 10.1039/c4cc00521j

DO - 10.1039/c4cc00521j

M3 - Journal article

C2 - 24584191

AN - SCOPUS:84901036335

SN - 1359-7345

VL - 50

SP - 6207

EP - 6210

JO - Chemical Communications

JF - Chemical Communications

IS - 47

ER -

A coumarin-based fluorescent probe for recognition of Cu²⁺ and fast detection of histidine in hard-to-transfect cells by a sensing ensemble approach

Abstract

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