A colorimetric and fluorescent turn-on chemosensor operative in aqueous media for Zn2+ based on a multifunctionalized spirobenzopyran derivative

Jian Fa Zhu, Han Yuan, Wing Hong CHAN*, Albert W M LEE

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

65 Citations (Scopus)

Abstract

By conjugating spiropyran chloride 8 with 2-amino-N-(quinolin-8-yl) acetamide (5), multifunctionalized spirobenzopyran derivative SPQN was designed and synthesized as a water soluble colorimetric and fluorescent turn-on chemosensor for Zn2+. In 50% aqueous ethanol buffer solution, SPQN displayed a selective chelation fluorescence enhancement (16-fold) at 650 nm and visible color change (from colorless to red) with Zn2+ among the metal ions examined. In addition, as the third channel to display the metal binding characteristics of SPQN, operating on an efficient FRET process between the quinoline and the merocyanine moiety of the sensor, ratiometric determination of Zn2+ can be realized.

Original languageEnglish
Pages (from-to)3957-3964
Number of pages8
JournalOrganic and Biomolecular Chemistry
Volume8
Issue number17
DOIs
Publication statusPublished - 7 Sep 2010

Scopus Subject Areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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