Keyphrases
2-Hydroxyglutarate (2-HG)
5%
Aggressive Phenotype
5%
Antiproliferative Activity
5%
Cancer Hallmarks
5%
Cancer Recurrence
5%
Cancer Tumor
5%
Cell Line Models
5%
Central Metabolic Pathways
5%
Citrate Synthase
100%
Clinical Analysis
5%
Colorectal Cancer
11%
Colorectal Cancer Cell Lines
5%
Colorectal Cancer Cells
5%
Colorectal Cancer Progression
100%
Colorectal Carcinogenesis
5%
Cycle Flux
5%
Dysregulation
5%
Enzymatic Function
5%
Epigenomics
5%
Functional Experiments
5%
Gene Signature
5%
Heterocomplex
17%
Homodimer
5%
In Silico Screening
5%
Metabolic Alterations
5%
Metabolic Reprogramming
5%
Mitochondria
5%
Mitochondrium
5%
Oncogenic Gene
5%
Oncometabolite
5%
Organoid Models
5%
Patients with Colorectal Cancer
5%
Small Molecules
5%
Splice Isoforms
5%
Splice Variant
100%
Strong Correlation
5%
Survival Outcomes
5%
Tricarboxylic Acid Cycle (TCA cycle)
100%
Tumor Growth
5%
Tumor Metastasis
5%
Medicine and Dentistry
2 Hydroxyglutaric Acid
5%
Antiproliferative Activity
5%
Cancer Cell
5%
Cancer Growth
100%
Cancer Recurrence
5%
Carcinogenesis
5%
Citrate Synthase
100%
Citric Acid Cycle
100%
Colorectal Cancer Cell Line
5%
Colorectal Carcinoma
100%
Enzyme Activity
5%
Homodimer
5%
In Silico
5%
In Vitro
5%
Malignant Neoplasm
5%
Metastatic Carcinoma
5%
Mitochondrion
5%
Oncogene
5%
Organoid
5%
Tumor
5%
Tumor Progression
5%
Upregulation
5%
Biochemistry, Genetics and Molecular Biology
Antiproliferative Activity
5%
Cancer Cell
11%
Carcinogenesis
5%
Citrate Synthase
100%
Citric Acid Cycle
100%
Enzyme Activity
5%
Gene Signature
5%
Isoform
17%
Metabolic Pathway
5%
Mitochondrion
5%
Oncogene
5%
Reprogramming
5%
Small Molecule
5%
Tumor Progression
5%
Upregulation
5%