A capsule review of recent studies on the application of mass spectrometry in the analysis of Chinese medicinal herbs

Zongwei CAI*, F. S.C. Lee, X. R. Wang, W. J. Yu

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

103 Citations (Scopus)

Abstract

Chinese herbal medicine is gaining increasing popularity worldwide as an alternative approach to the development of pharmaceuticals in therapeutic applications. Chemical characterization and compositional analysis of Chinese medicines provide the necessary scientific basis for the discovery and development of new drugs of natural origin. Applications of mass spectrometry in the analysis of Chinese herbal medicines have been growing rapidly in recent years owing to the rapid technical advances and increasing availability of the instrumentation. This paper reviews the current status of how different mass spectrometric techniques are being used to support research studies of Chinese medicines. The focus is on crude herbal medicines and their derived products. The review is not meant to be exhaustive, but rather to provide a general overview of the various research activities in this rapidly expanding field. In the discussion of specific herbs, the emphasis is placed on ginseng and Danshen, two of the herbs for which active experimental work is on-going in the authors' laboratories. Other selected herbs will be discussed only briefly, aiming, primarily to illustrate the current status of research in the area.

Original languageEnglish
Pages (from-to)1013-1024
Number of pages12
JournalJournal of Mass Spectrometry
Volume37
Issue number10
DOIs
Publication statusPublished - 1 Oct 2002

Scopus Subject Areas

  • Spectroscopy

User-Defined Keywords

  • Chinese medicinal herbs
  • Danshen
  • Ginseng
  • Mass spectrometry

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