A BODIPY-based fluorescent sensor for the detection of Pt2+ and Pt drugs

  • Fung Kit Tang
  • , Jiaqian Zhu
  • , Fred Ka Wai Kong
  • , Maggie Ng
  • , Qingyuan Bian
  • , Vivian Wing Wah Yam*
  • , Anfernee K W Tse*
  • , Yu Chung Tse*
  • , Ken C F Leung*
  • *Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

45 Citations (Scopus)

Abstract

A BODIPY-based fluorescent sensor PS with an NO4S2 podand ligand was studied for the selective detection of Pt2+ over 21 cations as well as selected platinum drugs in aqueous medium. The platinum sensor PS shows 28-fold, 22-fold and 14-fold fluorescence turn-on enhancements to Pt2+, cisplatin and nedaplatin, and was thereby employed to detect platinum drugs in A-549 human lung cancer cells.

Original languageEnglish
Pages (from-to)2695-2698
Number of pages4
JournalChemical Communications
Volume56
Issue number18
DOIs
Publication statusPublished - 4 Mar 2020

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