A BODIPY-based fluorescent sensor for the detection of Pt2+ and Pt drugs

Fung Kit Tang, Jiaqian Zhu, Fred Ka Wai Kong, Maggie Ng, Qingyuan Bian, Vivian Wing Wah Yam*, Anfernee K W TSE, Yu Chung Tse, Ken C F LEUNG

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A BODIPY-based fluorescent sensor PS with an NO4S2 podand ligand was studied for the selective detection of Pt2+ over 21 cations as well as selected platinum drugs in aqueous medium. The platinum sensor PS shows 28-fold, 22-fold and 14-fold fluorescence turn-on enhancements to Pt2+, cisplatin and nedaplatin, and was thereby employed to detect platinum drugs in A-549 human lung cancer cells.

Original languageEnglish
Pages (from-to)2695-2698
Number of pages4
JournalChemical Communications
Volume56
Issue number18
DOIs
Publication statusPublished - 4 Mar 2020

Scopus Subject Areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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