TY - JOUR
T1 - 1,3,5-Triazine tetrad-aza cyclophanes coated silica as a novel stationary phase for high performance liquid chromatography
AU - Zhang, Wenfen
AU - Wang, Fei
AU - Zhang, Yanhao
AU - Zhao, Wuduo
AU - Guo, Yi
AU - Wen, Wei
AU - Zhang, Shusheng
N1 - Funding information:
We acknowledge the support of National Natural Science Foundation of China, China (21775140,21475119, 21705143) and Henan Province outstanding scientific and technological innovation talent, China (184200510019).
Publisher Copyright:
© 2018 Elsevier B.V. All rights reserved.
PY - 2019/3/18
Y1 - 2019/3/18
N2 - A new stationary phase (TTCPSP) has been prepared by covalently bonding 1,3,5-triazine tetrad-aza cyclophanes (TTCP) onto silica gel using 3-aminopropyl triethoxysilane as the coupling reagent. The stationary phase developed in this way was characterized by IR spectroscopy, elemental analysis and thermogravimetric analysis. The chromatographic performance and retention mechanisms of the new stationary phase were validated and compared with octadecylsilyl (ODS) stationary phases using a variety of compounds including monosubstituted benzenes, polycyclic aromatic hydrocarbons (PAHs) and flavonoids. The results indicate that the 1,3,5-triazine tetrad-aza cyclophanes (TTCPSP) stationary phase addresses solutes with multiple interactions, such as hydrophobic, hydrogen bonding, π-π, and inclusion interactions. TTCPSP, which shows strong retention ability to compounds containing –OH, –NH2 or phenyl conjugate groups, is promising as a type of solid phase extraction sorbent.
AB - A new stationary phase (TTCPSP) has been prepared by covalently bonding 1,3,5-triazine tetrad-aza cyclophanes (TTCP) onto silica gel using 3-aminopropyl triethoxysilane as the coupling reagent. The stationary phase developed in this way was characterized by IR spectroscopy, elemental analysis and thermogravimetric analysis. The chromatographic performance and retention mechanisms of the new stationary phase were validated and compared with octadecylsilyl (ODS) stationary phases using a variety of compounds including monosubstituted benzenes, polycyclic aromatic hydrocarbons (PAHs) and flavonoids. The results indicate that the 1,3,5-triazine tetrad-aza cyclophanes (TTCPSP) stationary phase addresses solutes with multiple interactions, such as hydrophobic, hydrogen bonding, π-π, and inclusion interactions. TTCPSP, which shows strong retention ability to compounds containing –OH, –NH2 or phenyl conjugate groups, is promising as a type of solid phase extraction sorbent.
KW - 1,3,5-Triazine tetrad-aza cyclophanes
KW - Multiple interactions
KW - Retention mechanism
KW - Stationary phase
UR - http://www.scopus.com/inward/record.url?scp=85054155608&partnerID=8YFLogxK
U2 - 10.1016/j.seppur.2018.09.082
DO - 10.1016/j.seppur.2018.09.082
M3 - Journal article
AN - SCOPUS:85054155608
SN - 1383-5866
VL - 211
SP - 227
EP - 232
JO - Separation and Purification Technology
JF - Separation and Purification Technology
ER -
