毛萼紫薇化学成分研究

目的：研究毛萼紫薇（Lagerstroemia balansae Koehne）的化学成分。方法：采用各种色谱技术分离纯化化合物，并通过理化性质和波谱学方法鉴定化合物的结构。结果：从毛萼紫薇茎的95%乙醇提取物中分离得到7个化合物，分别鉴定为ficus-carpanoside A（Ⅰ）、反式-阿魏酸二十八烷酯（trans-ferulic acid octacosyl ester,Ⅱ）、lyoniside（Ⅲ）、gomisin N（Ⅳ）、正-三十烷醇（n-triacontanol,Ⅴ）、β-谷甾醇（β-sitosterol,Ⅵ）和胡萝卜苷（daucosterol,Ⅶ）。结论：以上化合物均为首次从该植物中获得，其中化合物ⅠⅤ为首次从紫薇属植物中分离得到。同时本实验还在2D-NMR的基础上对化合物Ⅰ在DMSO-d6中的1H-NMR和13C-NMR数据以及化合物Ⅰ在DMSO-d6中的1H-NMR数据进行了全归属，并纠正了文献中化合物Ⅲ13C-NMR数据的错误归属。 

OBJECTIVE: To study the chemical constituents of Lagerstroemia balansae Koehne. METHODS: The crude herb of the stems of L. balansae was extracted with 95% EtOH and isolated by repeated chromatographic methods. The structures of the isolated compounds were elucidated by physicochemical and spectral analysis. RESULTS: Seven compounds were yielded and identified as: ficuscarpanoside A(I), trans-ferulic acid octacosyl ester (II), lyoniside (III), gomisin N (IV), n-triacontanol (V), β-sitosterol (VI) and daucosterol (VII). CONCLUSION: All compounds were isolated from this plant for the first time, and compound (I-V) were obtained from the genus Lagerstroemia for the first time. On the basis of 2D-NMR spectra the ¹H and ¹³C-NMR signals of I, the ¹H-NMR signals of III in DMSO-d₆ were assigned totally and the uncorrected assignment of ¹³C-NMR signals of III in the literature were revised.