新型四齿膦配体在钯催化的Suzuki偶联反应中的应用

null 张愚; Tao 易韬; null 王堃; null 付海燕; null 陈华; null 李瑞祥

doi:10.6023/cjoc1108181

新型四齿膦配体在钯催化的Suzuki偶联反应中的应用

Translated title of the contribution: A new tetraphosphine and its application in Pd-catalyzed suzuki cross-coupling reaction

张愚^*, 易韬, 王堃, 付海燕, 陈华, 李瑞祥

^*Corresponding author for this work

School of Chinese Medicine

Research output: Contribution to journal › Journal article › peer-review

7 Citations (Scopus)

Abstract

A new tetraphosphine, N,N,N′,N′-tetra(diphenylphosphinomethyl)- cyclohexane-1,2-diamine (1) has been designed and synthesized from the commercially available cyclohexane-1,2-diamine as starting material. This tetraphosphine in combination with [Pd(η ³-C ₃H ₅)Cl] ₂ is a very efficient catalyst for Suzuki cross-coupling reaction. Various aryl- and heteroaryl-chlorides as well as aryl-, heteroaryl-, and alkyl-bromides could be successfully transformed to the desired products in up to 99% yield with 0.1 mol% catalyst loading.

Translated title of the contribution	A new tetraphosphine and its application in Pd-catalyzed suzuki cross-coupling reaction
Original language	Chinese (Simplified)
Pages (from-to)	790-793
Number of pages	4
Journal	有机化学
Volume	32
Issue number	4
DOIs	https://doi.org/10.6023/cjoc1108181
Publication status	Published - Apr 2012

Scopus Subject Areas

Organic Chemistry

User-Defined Keywords

Catalysis
Palladium
Phenylboronic acid
Suzuki cross-coupling
Tetraphosphine

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10.6023/cjoc1108181

Cite this

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title = "新型四齿膦配体在钯催化的Suzuki偶联反应中的应用",

abstract = "A new tetraphosphine, N,N,N′,N′-tetra(diphenylphosphinomethyl)- cyclohexane-1,2-diamine (1) has been designed and synthesized from the commercially available cyclohexane-1,2-diamine as starting material. This tetraphosphine in combination with [Pd(η 3-C 3H 5)Cl] 2 is a very efficient catalyst for Suzuki cross-coupling reaction. Various aryl- and heteroaryl-chlorides as well as aryl-, heteroaryl-, and alkyl-bromides could be successfully transformed to the desired products in up to 99% yield with 0.1 mol% catalyst loading.",

keywords = "Catalysis, Palladium, Phenylboronic acid, Suzuki cross-coupling, Tetraphosphine",

author = "张愚 and 易韬 and 王堃 and 付海燕 and 陈华 and 李瑞祥",

year = "2012",

month = apr,

doi = "10.6023/cjoc1108181",

language = "Chinese (Simplified)",

volume = "32",

pages = "790--793",

journal = "有机化学",

issn = "0253-2786",

publisher = "中国化学会;中国科学院上海有机化学研究所",

number = "4",

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TY - JOUR

T1 - 新型四齿膦配体在钯催化的Suzuki偶联反应中的应用

AU - 张愚, null

AU - 易韬, null

AU - 王堃, null

AU - 付海燕, null

AU - 陈华, null

AU - 李瑞祥, null

PY - 2012/4

Y1 - 2012/4

N2 - A new tetraphosphine, N,N,N′,N′-tetra(diphenylphosphinomethyl)- cyclohexane-1,2-diamine (1) has been designed and synthesized from the commercially available cyclohexane-1,2-diamine as starting material. This tetraphosphine in combination with [Pd(η 3-C 3H 5)Cl] 2 is a very efficient catalyst for Suzuki cross-coupling reaction. Various aryl- and heteroaryl-chlorides as well as aryl-, heteroaryl-, and alkyl-bromides could be successfully transformed to the desired products in up to 99% yield with 0.1 mol% catalyst loading.

AB - A new tetraphosphine, N,N,N′,N′-tetra(diphenylphosphinomethyl)- cyclohexane-1,2-diamine (1) has been designed and synthesized from the commercially available cyclohexane-1,2-diamine as starting material. This tetraphosphine in combination with [Pd(η 3-C 3H 5)Cl] 2 is a very efficient catalyst for Suzuki cross-coupling reaction. Various aryl- and heteroaryl-chlorides as well as aryl-, heteroaryl-, and alkyl-bromides could be successfully transformed to the desired products in up to 99% yield with 0.1 mol% catalyst loading.

KW - Catalysis

KW - Palladium

KW - Phenylboronic acid

KW - Suzuki cross-coupling

KW - Tetraphosphine

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U2 - 10.6023/cjoc1108181

DO - 10.6023/cjoc1108181

M3 - Journal article

AN - SCOPUS:84864564234

SN - 0253-2786

VL - 32

SP - 790

EP - 793

JO - 有机化学

JF - 有机化学

IS - 4

ER -

新型四齿膦配体在钯催化的Suzuki偶联反应中的应用

Abstract

Scopus Subject Areas

User-Defined Keywords

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