αvβ3-Isoform specific erbium complexes highly specific for bladder cancer imaging and photodynamic therapy

Yan Zhou, Chi Fai Chan, Daniel W J Kwong*, Ga Lai Law*, Steven Cobb, Rick Wai Kwok Wong*, Ka-Leung Wong*

*Corresponding author for this work

Research output: Contribution to journalJournal articlepeer-review

28 Citations (Scopus)

Abstract

We have synthesized a bifunctional erbium-porphyrin tumor imaging and PDT agent (Er-R3) that is capable of killing bladder cancer cells via its selective binding to the integrin αvβ3 isoform overexpressed on the cell membrane.

Original languageEnglish
Pages (from-to)557-560
Number of pages4
JournalChemical Communications
Volume53
Issue number3
Early online date6 Dec 2016
DOIs
Publication statusPublished - 11 Jan 2017

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