Keyphrases
Protopine
100%
Histone Deacetylase 6 (HDAC6)
75%
Alzheimer's Disease Model
66%
Pathological tau
58%
Tau Pathology
57%
Chaperone-mediated Autophagy
50%
Bromo
50%
Proteasomal Degradation
50%
Alzheimer's Disease Treatment
50%
Alzheimer's Disease
36%
3xTg-AD
19%
Anti-tau
16%
Brain Permeability
16%
Memory Function
16%
Tau Mouse Model
12%
Hsc70
12%
Phosphorylated tau
12%
Molecular Docking
12%
P301S
12%
Cognitive Loss
8%
HDAC6 Inhibitor
8%
IC50 Value
8%
Fold Increase
8%
Alkaloids
8%
Memory Loss
8%
Effective Therapy
8%
G-value
8%
Neuronal Cell Lines
8%
Anti-Alzheimer Drugs
8%
Small Molecules
8%
Therapeutic Strategies
8%
Molecular Chaperone
8%
Safe Therapy
8%
Alzheimer's Disease Patient
8%
Parent Compounds
8%
LAMP2
8%
Pharmacological Activities
8%
Binding Affinity
7%
Insoluble tau
7%
P301S Mice
7%
Pharmacology, Toxicology and Pharmaceutical Science
Protopine
100%
Alzheimer's Disease
100%
Histone Deacetylase 6
75%
Disease Model
62%
Combination Therapy
50%
Mouse Model
10%
Cell Culture
7%
Pharmacokinetic
7%
Amnesia
6%
Chaperone
6%
IC50
6%
Disease Activity
6%
Drug Action
6%
Biochemistry, Genetics and Molecular Biology
Tau
100%
Chaperone-Mediated Autophagy
50%
Histone Deacetylase
50%
HDAC6
18%
Memory
12%
Mouse Model
8%
Docking (Molecular)
8%
Binding Affinity
8%
Pharmacokinetic
8%
Heat Shock Protein
8%