Oral bioavailability of polysaccharides: an exploration of TLRs/Dectin-mediated phagocytosis to Ganoderma glucan GSP-2 by intestinal macrophages in vitro and in vivo

Keyphrases

1. Polysaccharide 100%
2. Oligosaccharides 40%
3. Dendrobium Officinale 29%
4. Dendrobium Officinale Polysaccharide 27%
5. Bioactive Polysaccharides 26%
6. LC-QTOF-MS 24%
7. Edible Bird's Nest 23%
8. Peyer's Patches 20%
9. Gut Microbiota 19%
10. Immune Response 19%
11. Macrophages 17%
12. Peptide Markers 15%
13. Astragalus Polysaccharide 15%
14. MS-MS 15%
15. Hyperbranched 15%
16. Heteroglycan 15%
17. Radix Astragali 12%
18. Cordyceps 11%
19. RAW264.7 Cells 11%
20. Glucan 11%
21. Mechanism of Action 10%
22. Balb C Mice 10%
23. Adulterants 10%
24. Highly Selective 9%
25. Lymphatics 9%
26. Radix Astragali Polysaccharides 9%
27. Oligosaccharide Analysis 9%
28. Phagocytosis 8%
29. Toll-like Receptor 4 (TLR4) 8%
30. Ganoderma Boninense 8%
31. Chemical Structure 8%
32. Herb Formula 8%
33. Ethyl Esters 8%
34. Immunomodulatory Effect 7%
35. Intestinal Macrophages 7%
36. Chemical Mechanism 7%
37. Structure-activity 7%
38. Dectin-1 7%
39. Lymphatic Absorption 7%
40. Antitumor Immune Response 7%
41. LC-QqQ-MS 7%
42. Scheduled multiple Reaction Monitoring 7%
43. Phenotypic Polarization 7%
44. Mannan 7%
45. Backbone Structure 7%
46. Notch Signaling Pathway 7%
47. Macrophage Phenotype 7%
48. Cordyceps Polysaccharide 7%
49. Modulatory Properties 7%
50. Polysaccharides from Ganoderma Lucidum 7%
51. Immunomodulating 7%
52. Oral Bioavailability 7%
53. Ganoderma 7%
54. Danggui Buxue Tang 7%
55. Stall 7%
56. Natural Polysaccharides 7%
57. Chemotherapy-induced Myelosuppression 7%
58. Carbohydrates 7%
59. Product Basis 7%
60. Tumor Growth 7%
61. Food Authentication 7%
62. Myeloid Differentiation Factor 88 (MyD88) 7%
63. Rapid Authentication 7%
64. Gelatin 7%
65. Interferon Regulatory Factor 3 (IRF3) 7%
66. Hematopoietic Stem Cells 7%
67. Comprehensive Comparison 7%
68. Oral Dosing 7%
69. Liquid Chromatography Quadrupole Time-of-flight Mass Spectrometry 7%
70. Oral Administration 7%
71. Ultra-high Performance Liquid Chromatography (UHPLC) 7%
72. Anti-fatigue 7%
73. Astragalus 7%
74. Ultra-performance Liquid Chromatography Coupled with Quadrupole Time-of-flight Mass Spectrometry 7%
75. Herbal Formula 7%
76. Macrophage Activation 7%
77. Recent Advances 7%
78. Toll-like 7%
79. Natural Medicine 7%
80. Natural Bioactive Compounds 7%
81. Antitumor 7%
82. Ejiao 7%
83. Donkey 7%
84. M Cells 7%
85. Uncariae Ramulus Cum Uncis 7%
86. Fluorescent Labeling 7%
87. Bioactivity 7%
88. Repeatability 6%
89. Rhodiola Rosea Extract 6%
90. Bone Marrow 6%
91. Specific Marker 5%
92. Dendritic Cells 5%
93. Starch 5%
94. M1 Phenotype 5%
95. Immune Cells 5%
96. Macrophage Polarization 5%