Mass spectrometry-based metabolomics investigation on lung toxicity induced by microplastics exposure from air particulates

Keyphrases

1. Microplastics 100%
2. Quinones 98%
3. Para-phenylenediamine 68%
4. P-phenylenediamine 66%
5. 6-PPDQ 57%
6. Mass Spectrometry 56%
7. Emerging Contaminants 42%
8. Transformation Products 33%
9. Hong Kong 32%
10. Wastewater Treatment Plant 32%
11. Soil Nematodes 32%
12. Nematode Caenorhabditis Elegans 32%
13. Inhalation 27%
14. Human Health 26%
15. Tire 24%
16. Nanoplastics 24%
17. Lung 21%
18. Health Implications 21%
19. Antioxidant 20%
20. House Dust 19%
21. Human Exposure 18%
22. Airborne Particulate Matter 18%
23. Tire Wear 18%
24. Human Urine 17%
25. Mass Spectrometry-based Metabolomics 16%
26. Dust Level 16%
27. UV-induced 16%
28. Aquatic Bacteria 16%
29. Kinetic Product 16%
30. Product Toxicity 16%
31. In Vivo Distribution 16%
32. Microplastic Exposure 16%
33. Airborne Microplastics 16%
34. UPLC-HRMS 16%
35. Lung Toxicity 16%
36. Metabolism 16%
37. Photodegradation 16%
38. Nanoparticle Toxicity 16%
39. Metabolomics 16%
40. Diagnostic Ions 16%
41. Recent Applications 16%
42. Polystyrene Nanoplastics (PS-NPs) 16%
43. Fragmentation Pattern 16%
44. Acute Effects 16%
45. Terrestrial Ecosystems 16%
46. L02 Cells 16%
47. Particulate Matter 2.5 (PM2.5) 16%
48. Human Urine Samples 16%
49. Tire Rubber 16%
50. ITRAQ Analysis 16%
51. Human Body 16%
52. 6PPD-quinone 16%
53. Ion Loss 16%
54. Mitochondrial Damage 16%
55. Screening Strategy 16%
56. Product Identification 16%
57. Machine Learning 16%
58. Neutral Loss 16%
59. Toxicity Assessment 16%
60. Human Liver Cells 16%
61. Stable Isotopes 16%
62. Pattern-based 16%
63. Human Lung Cells 16%
64. Mechanistic Insight 16%
65. Metabolic Function 16%
66. Polyfluoroalkyl Substances 16%
67. Indoor Dust 16%
68. BEAS-2B Cells 16%
69. Absorption Distribution Metabolism Excretion 16%
70. Aqueous Environment 16%
71. Road Wear 16%
72. Spatial Exposure 16%
73. Tire Additives 16%
74. Urban Road Dust 16%
75. Wear Particles 16%
76. Additive Chemicals 16%
77. First-ever 16%
78. Spatial Association 16%
79. Spatial Distribution 16%
80. Phosphorylation 16%
81. 6PPD 16%
82. COVID-19 Pandemic 16%
83. Kinetic Profile 16%
84. Biotransformation 16%
85. Face Mask Use 16%
86. Metropolis 16%
87. Environmental Correlates 16%
88. Southern China 16%
89. Coastal Waters 16%
90. Microplastic Pollution 16%
91. Pregnant Women 16%
92. Trimester 16%
93. Pattern Variability 16%
94. Multiple Countries 16%
95. Plasticizer 16%
96. Molecular Sensing 16%
97. Electronics-free 16%
98. Mini-tablets 16%
99. Pollutants 12%
100. Caenorhabditis Elegans 12%
101. Effluent 11%
102. Victoria Harbour 10%
103. Oyster Culture 10%
104. Biosphere 10%
105. Metabolic Toxicity 10%
106. Environmental Levels 10%
107. Toxicity Pathways 10%
108. Metabolic Pathway 10%
109. Microplastic Sources 9%
110. Liver 9%
111. Non-target Screening 9%
112. Urine Samples 8%
113. Plastic Debris 8%
114. Transmission Electron Microscopy Analysis 8%
115. Proteome Dynamics 8%
116. Mitochondrial Respiration 8%
117. Mitochondrial Function 8%
118. Mitochondrial Dysfunction 8%
119. Sample Pretreatment 8%
120. Matrix Effect 8%
121. Mean Concentration 8%
122. Chromatography 8%
123. Functional Pathways 8%
124. Overproduction 8%
125. Mitochondria 8%
126. Linear Relationship 8%
127. Human Cells 8%
128. Liquid-liquid Extraction 8%
129. Limit of Detection 8%
130. Ultra-high Performance Liquid Chromatography (UHPLC) 8%
131. Highest Good 8%
132. Adverse Outcomes 8%
133. Linear Correlation Coefficient 8%
134. Relative Standards 8%
135. High-resolution Mass 8%
136. Untargeted Metabolomics 8%
137. Normal Human 8%
138. Mitochondrial Reactive Oxygen Species (mtROS) 8%
139. Mitochondrial Membrane Potential 8%
140. Good Repeatability 8%
141. Cell Death 8%
142. High Sensitivity 8%
143. Mitochondrium 8%
144. Phthalate Esters 8%
145. High Concentration 7%
146. Surface Water 7%
147. Environmental Compartments 6%
148. Terrestrial Environment 6%
149. Chemical Derivatives 6%
150. Adverse Effects 6%
151. Hazard Quotient 5%
152. Composition Profile 5%
153. Liquid Chromatography-high Resolution Mass Spectrometry (LC-HRMS) 5%
154. Source Composition 5%
155. Low Density Polymers 5%
156. Styrofoam 5%
157. Potential Pollution Sources 5%
158. Tracing Source 5%
159. Abundance Trends 5%
160. Sewage Outfall 5%
161. Marine Pollutants 5%
162. Raft 5%
163. Microplastic Abundance 5%
164. Culture Areas 5%
165. River Runoff 5%
166. Local Environmental Factors 5%
167. Multivariate Analysis 5%
168. Dense Urban Areas 5%
169. Chlorophyll a (Chl a) 5%
170. High Abundance 5%
171. Hong Kong Waters 5%
172. Sewage Treatment Plant 5%
173. Polyethylene Terephthalate 5%
174. Estuary 5%
175. Polyvinyl Chloride 5%
176. Polyethylene 5%
177. Polypropylene 5%
178. High Performance Polymers 5%
179. Polystyrene 5%
180. Escherichia Coli 5%
181. Environmental Determinants 5%
182. Deep Bay 5%
183. Human Activities 5%
184. Radiofrequency 5%
185. Metal Disc 5%
186. Wireless Actuation 5%
187. Curvature Adaptive 5%
188. Mechanical Mismatch 5%
189. Biocompatible Materials 5%
190. Gliding Motion 5%
191. Molecular Sampling 5%
192. PH-sensitive Hydrogel 5%
193. Untargeted Metabolomics Profiling 5%
194. Viscous Environment 5%
195. Fluid Samples 5%
196. Biomarker Sensing 5%
197. United States 5%
198. Health Risk 5%