Development of novel inhibitors targeting the resistance mechanisms of clinical superbugs

Keyphrases

1. Iridium 100%
2. Iridium Complex 73%
3. G-quadruplex 61%
4. Luminescent Probe 51%
5. Iridium(III) Complex 49%
6. Long-lived 46%
7. Virtual Screening 38%
8. Cancer Cells 35%
9. Limit of Detection 32%
10. Cancer Therapy 31%
11. Living Cells 31%
12. Switch-off 30%
13. Chemosensor 29%
14. Protein-protein Interaction 29%
15. Natural Products 28%
16. Transition Metal Complexes 28%
17. Cancer Treatment 27%
18. Long Lifetime 26%
19. Luminescence 26%
20. Pin1 Inhibitor 25%
21. Luminescent Chemosensor 25%
22. Reaction-based 25%
23. Metal Complexes 24%
24. Large Stokes Shift 21%
25. In Cancer 21%
26. Neurodegenerative Diseases 20%
27. Photophysical Properties 19%
28. Pin1 19%
29. Proteinase Inhibitor 19%
30. Iridium(III) 19%
31. Graphene Oxide 19%
32. Base Metals 17%
33. Aqueous Solution 17%
34. Disease Diagnosis 17%
35. Metal Ions 17%
36. Time-resolved Emission Spectroscopy 16%
37. Inhibitor Discovery 15%
38. Dual-functional 15%
39. Long-lived Phosphorescence 15%
40. Rapid Detection 14%
41. High Specificity 13%
42. Therapeutic Agents 13%
43. Amplification System 12%
44. Cervical Cancer Prevention 12%
45. Molecular Strategies 12%
46. Circulating Tumor Cells 12%
47. Complex Biological Systems 12%
48. Glyphosate 12%
49. Iridium Dimers 12%
50. Cell Analysis 12%
51. Periodate 12%
52. Aurone Derivatives 12%
53. Metal Homeostasis 12%
54. Keap1-Nrf2 12%
55. Metal Dyshomeostasis 12%
56. Oxalyl Chloride 12%
57. Suspension Droplet 12%
58. Protein Biomarker Detection 12%
59. Diethyldithiocarbamate 12%
60. Metal Ion Detection 12%
61. Drug Repurposing 12%
62. System Integration 12%
63. Uracil-DNA Glycosylase 12%
64. Vps34 12%
65. VEGF165 12%
66. Senescence 12%
67. Hepatitis B Virus 12%
68. Oligonucleotides 12%
69. Droplet Mode 12%
70. NF-B 12%
71. Photoluminescence 12%
72. Dibenzothiophene 12%
73. In Situ 12%
74. Biological Environment 12%
75. Water Samples 12%
76. Real-time Detection 12%
77. NEDD8-activating Enzyme 12%
78. Cell Cycle Arrest 12%
79. Anticancer Activity 12%
80. Chemoselective 12%
81. Metal Probe 12%
82. Biomolecule Detection 12%
83. Breast Cancer Cell Lines 12%
84. Carbon Disulfide 12%
85. Low-toxic 12%
86. Medical Diagnostics 12%
87. Disease-related 12%
88. Pharmacological Inhibitors 12%
89. Off-on 12%
90. Anti-melanoma 12%
91. Ubiquitination 12%
92. Virus Gene 12%
93. Autophagy 12%
94. Receptor-interacting Protein Kinase 1 (RIPK1) 12%
95. Neuraminidase 12%
96. Bromodomain-containing Protein 4 (BRD4) 12%
97. LSD1 12%
98. Time-resolved 12%
99. KDM5A 12%
100. Bioluminescent Assay 12%
101. Prostate Cancer Cells 12%
102. Split G-quadruplex 12%
103. Prostate Cancer 12%
104. Doxorubicin 12%
105. Ochratoxin A 12%
106. Fluorescent Nanoprobe 12%
107. Imaging Agents 12%
108. Microfluidic Device 12%
109. Screening Assays 12%
110. Lysosome 12%
111. Nitric Oxide 12%
112. Small Molecules 12%
113. Betaine 12%
114. Screening Approach 12%
115. Label-free Method 12%
116. Alkyl Halides 12%
117. Alzheimer's Disease Treatment 12%
118. Microfluidics 12%
119. Protector 12%
120. Melanoma Treatment 12%
121. Alzheimer's Disease 12%
122. Structure-guided 12%
123. Adsorption 12%
124. Hepatitis B Virus DNA 12%
125. Ultrasensitive Detection 12%
126. Polymerase Chain Reaction 12%
127. Behavioral Effects 12%
128. Electrochemiluminescence 12%
129. Gastrin-releasing Peptide Receptor (GRPr) 12%
130. Single-stranded DNA (ssDNA) 12%
131. Metal-organic Frameworks (MOFs) 12%
132. Immune Cells 12%
133. Guided Discovery 12%
134. Theranostic Imaging 12%
135. Theranostics 12%
136. Food Contamination 12%
137. High Selectivity 12%
138. Protein Biomarkers 11%
139. Oxide Systems 10%
140. Biomolecules 10%
141. Protein Partners 9%
142. Modified GO 9%
143. Malignant Tumor 9%
144. High Sensitivity 9%
145. Organic Dyes 9%
146. Luminescence Signal 9%
147. Sensitive Detection 8%
148. Natural Product Scaffold 8%
149. Thiourea 8%
150. Human Disease 8%
151. Emission Lifetime 7%
152. Time Use 7%
153. 5-fluorouracil (5-FU) 7%
154. Sodium Nitroprusside 7%
155. Maladies 7%
156. Clinical Application 7%
157. Cyclometalated Iridium(III) Complex 7%
158. Conjugation 7%
159. Cytotoxicity 7%
160. Signal-to-noise Ratio 6%
161. Overexpressing 6%
162. Background Fluorescence 6%
163. Cervical Cancer Cells 6%
164. S100B 6%
165. Iridium Metal 6%
166. Double-amidation Reactions 6%
167. Oxidative Stress 6%
168. Ambient Temperature 6%
169. Enhanced Emission 6%
170. Cervical Cancer 6%
171. Time Monitoring 6%
172. Fluorescence Detection 6%
173. Methylthiol 6%
174. Biomolecular 6%
175. Chemical Characteristics 6%
176. Metal Center 6%
177. Fluorescence Method 6%
178. Luminescence Response 6%
179. Organic Synthesis 6%
180. Red Luminescence 6%
181. Diamino 6%
182. Smartphone 6%
183. FDA-approved Drugs 6%
184. Biological Characteristics 6%
185. Imaging Probe 6%
186. Highly Sensitive 6%
187. Capture Probe 6%
188. Living Systems 6%
189. Contamination Analysis 6%
190. Metastasis 5%
191. Target Analyte 5%
192. Protein Degradation 5%
193. Cell-based 5%
194. Drug Discovery 5%
195. Cell-free 5%
196. Recent Advances 5%
197. Enzyme Activity 5%
198. Strand Displacement Amplification 5%
199. Detection Method 5%
200. Induced Apoptosis 5%