Constraint-based genome-scale computational modeling of human enterotype-associated gut commensal metabolism: Focus on the systems metabolic picture of bacterium Prevotella copri

In this project, we aim to reconstruct the genome-scale metabolic network model of Prevotella copri in combination with culture experiments and -omics data profiling. We will simulate this model for the enterotype-related inter-species interaction and predict the species-specific growth-limiting substrates.