Projects per year
Personal profile
Chinese Name
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Development of Small-molecule Inhibitors Targeting Sclerostin Loop3 for Osteoporosis
1/04/23 → 31/03/25
Project: Research project
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Osteoblastic sclerostin loop3-LRP4 interaction could be required by sclerostin to inhibit bone formation
1/01/25 → 31/12/27
Project: Research project
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Intracellular sclerostin plays a vital role in tumor progression and metastasis in triple-negative breast cancer
Sun, M., Qiao, S., Luo, H., Yang, X., Yang, L., Zhang, H., Chen, Z., Wang, L., Tao, X., Yu, Y., Ma, Y., Yuan, F., Ma, D., Chen, Q., Lu, A., Zhang, B. T., Zhang, G. & Li, F., 1 Feb 2024, In: Cancer Research. 84, 3, Supplement 1, B044.Research output: Contribution to journal › Conference article › peer-review
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Sclerostin inhibition in rare bone diseases: Molecular understanding and therapeutic perspectives
Tao, X., Wang, L., Yang, X., Jiang, H., Zhang, N., Zhang, H., Li, D., Li, X., Zhang, Y., Wang, S., Zhong, C., Yu, S., Ren, M., Sun, M., Li, N., Chen, T., Ma, Y., Li, F., Liu, J., Yu, Y., & 3 others , Jul 2024, In: Journal of Orthopaedic Translation. 47, p. 39-49 11 p.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Targeting osteoblastic 11β-HSD1 to combat high-fat diet-induced bone loss and obesity
Zhong, C., Li, N., Wang, S., Li, D., Yang, Z., Du, L., Huang, G., Li, H., Yeung, W. S., He, S., Ma, S., Wang, Z., Jiang, H., Zhang, H., Li, Z., Wen, X., Xue, S., Tao, X., Li, H., Xie, D., & 22 others , 4 Oct 2024, In: Nature Communications. 15, 1, 18 p., 8588.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Unique quinoline orientations shape the modified aptamer to sclerostin for enhanced binding affinity and bone anabolic potential
Gubu, A., Ma, Y., Yu, S., Zhang, H., Chen, Z., Ni, S., Abdullah, R., Xiao, H., Zhang, Y., Dai, H., Luo, H., Yu, Y., Wang, L., Jiang, H., Zhang, N., Tian, Y., Li, H., Lu, A., Zhang, B. & Zhang, G., 12 Mar 2024, In: Molecular Therapy Nucleic Acids. 35, 1, 14 p., 102146.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
A bimolecular modification strategy for developing long-lasting bone anabolic aptamer
Zhang, H., Yu, S., Ni, S., Gubu, A., Ma, Y., Zhang, Y., Li, H., Wang, Y., Wang, L., Zhang, Z., Yu, Y., Lyu, A., Zhang, B. & Zhang, G., 12 Dec 2023, In: Molecular Therapy - Nucleic Acids. 34, 18 p., 102073.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus)
Press/Media
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From Molecular Target to Aptamer Drug Discovery towards US-FDA Orphan Drug Designation
Yuanyuan YU, Ge ZHANG, Aiping LYU & Luyao WANG
19/12/22 → 20/12/22
4 Media contributions
Press/Media