Research output per year
Research output per year
Personal profile
Chinese Name
翟李翔
Research Interests
- Investigation of gut microbiota in the development of non-communicable diseases including functional gastrointestinal disorders, metabolic disorders and mental disorders.
- Investigation of Chinese medicine for the treatment of gut dysbiosis-induced metabolic disorders and functional gastrointestinal disorders.
- Metabolomics and lipidomics analysis of medicinal plants for pharmacological research and quality evaluation studies.
Biography
Dr. Lixiang Zhai obtained his B.Sc. in Pharmacy in Chinese Medicine from Guangdong Pharmaceutical University in 2015 and his Ph.D. in Chinese Medicine from Hong Kong Baptist University in 2021. He received his postdoctoral training at the Centre for Chinese Herbal Medicine Drug Development Limited (@InnoHK) from 2021-2022. He is currently a Research Assistant Professor at School of Chinese Medicine, Hong Kong Baptist University.
Dr. Zhai’s research focuses on the interactions between host and gut microbiota that underlie the development of functional bowel disorders, metabolic syndrome and mental disorders. He is also focused on the clinical translational research of Chinese medicine in the treatment of gastrointestinal diseases including irritable bowel syndrome and inflammatory bowel disease.
Dr. Zhai has published a series of articles in journals including Cell Host&Microbe, Nature Metabolism, Nature Communications, Journal of Clinical Investigation, Phytomedicine, Phytotherapy Research, Biomedicine & Pharmacotherapy and Food & Function.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Lixiang ZHAI is active. Topic labels come from the works of this scholar.
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Collaborations and top research areas from the last five years
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Gut microbiota-derived tryptamine and phenethylamine impair insulin sensitivity in metabolic syndrome and irritable bowel syndrome
Zhai, L., Xiao, H., Lin, C., Wong, H. L. X., Lam, Y. Y., Gong, M., Wu, G., Ning, Z., Huang, C., Zhang, Y., Yang, C., Luo, J., Zhang, L., Zhao, L., Zhang, C., Lau, J. Y-N., Lu, A., Lau, L-T., Jia, W., Zhao, L., & 1 others, 17 Aug 2023, In: Nature Communications. 14, 1, 14 p., 4986.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis
Zhai, L., Huang, C., Ning, Z., Zhang, Y., Zhuang, M., Yang, W., Wang, X., Wang, J., Zhang, L., Xiao, H., Zhao, L., Asthana, P., Lam, Y. Y., Chow, C. F. W., Huang, J. D., Yuan, S., Chan, K. M., Yuan, C. S., Lau, J. Y. N., Wong, H. L. X., & 1 others, 11 Jan 2023, In: Cell Host and Microbe. 31, 1, p. 33-44.e5 12 p.Research output: Contribution to journal › Journal article › peer-review
13 Citations (Scopus) -
Therapeutic effects and mechanisms of Zhen-Wu-Bu-Qi Decoction on dextran sulfate sodium-induced chronic colitis in mice assessed by multi-omics approaches
Zhai, L., Peng, J., Zhuang, M., Chang, Y. Y., Cheng, K. W., Ning, Z. W., Huang, T., Lin, C., Wong, H. L. X., Lam, Y. Y., Tan, H. Y., Xiao, H. T. & Bian, Z. X., May 2022, In: Phytomedicine. 99, 154001.Research output: Contribution to journal › Journal article › peer-review
Open Access5 Citations (Scopus) -
Cyclocarya paliurus leaves tea improves dyslipidemia in diabetic mice: A lipidomics-based network pharmacology study
Zhai, L., Ning, Z. W., Huang, T., Wen, B., Liao, C. H., Lin, C. Y., Zhao, L., Xiao, H. & Bian, Z., 28 Aug 2018, In: Frontiers in Pharmacology. 9, AUG, 973.Research output: Contribution to journal › Journal article › peer-review
Open Access49 Citations (Scopus) -
Ex Vivo and in Situ Evaluation of 'Dispelling-Wind' Chinese Medicine Herb-Drugs on Intestinal Absorption of Chlorogenic Acid
Zhai, L., Shi, J., Xu, W., Heinrich, M., Wang, J. & Deng, W., Dec 2015, In: Phytotherapy Research. 29, 12, p. 1974-1981 8 p.Research output: Contribution to journal › Journal article › peer-review
16 Citations (Scopus)