Personal profile
Chinese Name
Biography
Prof. Yu received his undergraduate education at the Henan University of Traditional Chinese Medicine, and obtained his PhD degree in biochemistry from the Hong Kong University of Science and Technology. Before joining the Hong Kong Baptist University, Prof. Yu once worked at China Pharmaceutical University, Nagasaki University, Hong Kong University of Science and Technology, Xiamen University and University of Macau. Prof. Yu is known for his research in herbal pharmacology, and in processing of Chinese medicinal materials. He has published more than 200 peer-reviewed research papers.
Consun Pharmaceutical Group Limited and Laboratory JaneClare Limited in collaboration with Prof. Yu's team established "Consun Chinese Medicines Research Centre for Renal Diseases" and "JaneClare Transdermal TCM Therapy Laboratory", respectively, in Hong Kong Baptist University.
Prof. Yu serves as Editorial Board Member/Associate Editor/Executive Editor/ Consulting Editor for more than 30 journals, e.g. LiShizhen Medicine and Materia Medica Research, BMC Complementary Medicine and Therapies, Current Topics in Nutraceutical Research, Journal of Alternative, Complementary & Integrative Medicine, Pharmacological Research.
Research Interests
1) Pharmacology of Chinese medicines, focusing on the mechanisms of action of anticancer, anti-inflammation and melanogenesis-modulation herbs; 2) Unique processing of Chinese medicinal herbs, focusing on the mechanisms underlying processing of Chinese medicines, standardization of adjuvant materials for the processing of Chinese medicinal herbs, and quality control of decoction pieces.
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Collaborations and top research areas from the last five years
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Atractylenolide II sensitizes hepatocellular carcinoma to sorafenib and reduces sorafenib-induced hepatotoxicity: a preclinical pharmacological study
FU, X. (PI) & YU, Z. (CoI)
1/01/26 → 31/12/28
Project: Research project
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Targeting PAX2: A Novel Therapeutic Strategy for Rectal Cancer as an Aging-Related Disease
YU, Z. (PI)
1/11/25 → 31/10/28
Project: Research project
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靶向DNA复制起始蛋白的共同转录因子PAX2治疗癌症 Targeting PAX2, a common transcriptional regulator of DNA replication-initiation proteins, for treating cancer
YU, Z. (PI), FU, X. (CoI), WANG, L. (CoI), WANG, X. (CoI) & WU, J. (CoI)
1/01/24 → 31/12/26
Project: Research project
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Does dihydroartemisinin overcome vemurafenib resistance in melanoma by suppressing FLI1 expression?
YU, Z. (PI)
1/01/23 → …
Project: Research project
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Si-Jun-Zi-Tang potentiates temozolomide's anti-melanoma efficacy and reduces its hepatotoxicity
Li, A. S. M., Wang, L., Fan, X.-Y., Wang, X.-Q., Wu, Y., Wu, J.-Y., Bai, J.-X., Han, R.-X., He, J.-J., Fu, X.-Q. & Yu, Z.-L., Apr 2026, In: Phytomedicine. 153, 17 p., 158012.Research output: Contribution to journal › Journal article › peer-review
Open Access -
30th Anniversary of Phytomedicine: Looking Back and Forth
Efferth, T., Zacchino, S., Georgiev, M., He, R.-R., Shen, X., Albrecht, U., Belwal , T., Bhutia, S. K., Chatterjee, M., Chen, J., Chen, Z.-Y., Cho, W., Devi, S. I., Eid, A. H., Orhan, I. E., Gao, Y., Hosseinzadeh, H., Hua, Q., Khan, H. & Kuete, V. & 22 others, , Dec 2025, In: Phytomedicine. 149, 4 p., 157525.Research output: Contribution to journal › Journal article
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Alisol B alleviates MASLD by activating liver autophagy and fatty acid oxidation via Ces2a
Zhang, C., Chen, L., Jiang, Y., Qiu, J., Lin, Y., Ren, G., Xu, F., Xi, J., Yu, Z., Rong, X. & Dou, X., 5 Jun 2025, In: International Immunopharmacology. 157, 14 p., 114768.Research output: Contribution to journal › Journal article › peer-review
3 Citations (Scopus) -
Alisol B ameliorated metabolic dysfunction-associated steatotic liver disease via regulating purine metabolism and restoring the gut microbiota disorders
Yiyou, L. (Co-first author), Congcong, Z. (Co-first author), Guilin, R. (Co-first author), Jiannan, Q., Yilong, F., Fucai, L., Qingsheng, L., Zhiling, Y., Lin, C. & Xiaobing, D., Sept 2025, In: Phytomedicine. 145, 19 p., 156992.Research output: Contribution to journal › Journal article › peer-review
2 Citations (Scopus) -
Aptamer-mediated liver-targeted curcumin delivery system based on tetrahedral framework nucleic acids for NAFLD
Chen, S., Liu, Y., Ma, S., Chen, L., Zhou, L., Wang, J., Huang, Y., Yu, Z. & Dou, X., 31 Dec 2025, In: Drug Delivery. 32, 1, 15 p., 2576222.Research output: Contribution to journal › Journal article › peer-review
Open Access
Prizes
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File
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Certificate for Excellence for an abstract presented at the 2022 World Federation of Chinese Medicine Societies Meeting
FAN, X. (Recipient), WU, Y. (Recipient), FU, X. (Recipient) & YU, Z. (Recipient), 23 Jun 2023
Prize: Award
File
Activities
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灵芝改善睡眠的有效成分研究
YU, Z. (Speaker)
12 Apr 2024Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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药食同源中草药在认知障碍中的应用
YU, Z. (Speaker)
7 Jun 2024Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Trends in Immunotherapy (Journal)
YU, Z. (Editor in chief)
Jan 2024 → …Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Current Traditional Medicine (Journal)
YU, Z. (Member of editorial board)
Jan 2024 → …Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Molecular mechanisms of TCM to treat cancer.
YU, Z. (Speaker)
24 Aug 2024Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units