Projects per year
Personal profile
Chinese Name
邓志强
Biography
Dr. DENG Zhiqiang received his Ph.D degree from Wuhan University in 2017. From 2015 to 2017, he studied at the Icahn Mount Sinai School of Medicine in the United States as a joint doctoral student. After obtaining his Ph.D degree, he received postdoctoral training at the Icahn Mount Sinai School of Medicine in the United States from 2017 to 2020. In 2021, he was engaged in research work in the University of Macau. In 2022, he joined the School of Chinese Medicine in Hong Kong Baptist University as a Research Assistant Professor.
Research Interests
Dr. Deng mainly focuses on the regulation of selective autophagy and autophagy receptors in neurodegenerative diseases (AD, PD, ALS), and the research on the regulation of autophagy activity and the neuroprotective mechanism by natural traditional Chinese medicine small molecules.
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Dive into the research topics where Zhiqiang DENG is active. Topic labels come from the works of this scholar.
- 3 Similar Scholars
Collaborations and top research areas from the last five years
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Projects
- 5 Active
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A novel mechanism of autophagy-lysosome pathway impairment in Alzheimer disease-associated neuropathogenesis: Role of AKAP11-mediated autophagy and PKA signaling
DENG, Z. (PI), Yue, Z. (CoI) & LI, M. (CoI)
1/01/26 → 31/12/28
Project: Research project
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基于TFEB介导的自噬通路探究AKAP11基因缺失导致精神分裂症的发病机制
DENG, Z. (PI), LI, M. (Collaborator), Kan , Y. (Collaborator), LIU, J. (Collaborator), GUAN, X. (Collaborator), LU, J. (Collaborator) & XU, X. (Collaborator)
1/01/26 → 31/12/28
Project: Research project
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外泌体介导的自噬诱导剂靶向神经元治疗阿尔茨海默病的临床前研究
LI, M. (PI), Ye, K. (CoPI), YANG, Z. (CoPI), DENG, Z. (CoPI) & IYASWAMY, A. (CoPI)
3/11/25 → 2/11/27
Project: Research project
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Investigating the mechanism of (-)Schisandrin B on the treatment of Parkinson's disease via regulating ATG16L1/NLRP3 signalling pathway
LI, M. (PI), Song, J.-X. (CoI), IYASWAMY, A. (CoI) & DENG, Z. (CoI)
9/10/24 → 8/10/27
Project: Research project
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Schizophrenia and bipolar disorder risk gene AKAP11 sustains cognitive function by regulating TFEB-mediated autophagy
Deng, Z. (Co-first author), Kan, Y. (Co-first author), Liu, J., Ying, K. Y., Yang, Y., Guan, X., Xu, X., Su, C., Lu, J., Lu, K., Chen, Y., Krishnamoorthi, S., Lu, J., Iyaswamy, A., Cheung, K. H., Song, J., Yue, Z. & Li, M., 16 Jul 2026, (E-pub ahead of print) In: Cell Death and Differentiation.Research output: Contribution to journal › Journal article › peer-review
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Corynoxine promotes TFEB/TFE3-mediated autophagy and alleviates Aβ pathology in Alzheimer’s disease models
Guan, X.-J., Deng, Z.-Q., Liu, J., Su, C.-F., Tong, B. C. K., Zhu, Z., Sreenivasmurthy, S. G., Kan, Y.-X., Lu, K., Chu, C. P. K., Pi, R.-B., Cheung, K.-H., Iyaswamy, A., Song, J.-X. & Li, M., May 2024, In: Acta Pharmacologica Sinica. 45, 5, p. 900–913 14 p.Research output: Contribution to journal › Journal article › peer-review
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Molecular engineering of a theranostic molecule that detects Aβ plaques, inhibits Iowa and Dutch mutation Aβ self-aggregation and promotes lysosomal biogenesis for Alzheimer's disease
Iyaswamy, A., Wang, X., Zhang, H., Vasudevan, K., Wankhar, D., Lu, K., Krishnamoorthi, S., Guan, X.-J., Su, C.-F., Liu, J., Kan, Y., Jaganathan, R., Deng, Z., Li, H. W., Wong, M. S. & Li, M., 21 Aug 2024, In: Journal of Materials Chemistry B. 12, 31, p. 7543-7556 14 p.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile -
Editorial: Autophagy in diseases—From basic to clinic
Yang, J., Ni, Z., Pi, H., Bohnert, A. & Deng, Z., 4 Jan 2023, In: Frontiers in Physiology. 13, 3 p., 1115511.Research output: Contribution to journal › Editorial
Open Access -
PPARɑ Ligand Caudatin Improves Cognitive Functions and Mitigates Alzheimer’s Disease Defects By Inducing Autophagy in Mice Models
Krishnamoorthi, S., Iyaswamy, A., Sreenivasmurthy, S. G., Thakur, A., Vasudevan, K., Kumar, G., Guan, X.-J., Lu, K., Gaurav, I., Su, C.-F., Zhu, Z., Liu, J., Kan, Y., Jayaraman, S., Deng, Z., Chua, K. K., Cheung, K.-H., Yang, Z., Song, J.-X. & Li, M., Sept 2023, In: Journal of NeuroImmune Pharmacology. 18, 3, p. 509-528 20 p.Research output: Contribution to journal › Journal article › peer-review
Open AccessFile
Activities
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The 2nd Guangdong-Hong Kong-Macao Greater Bay Area Neuroscience Conference
DENG, Z. (Participant)
29 Jan 2026 → 31 Jan 2026Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Advanced Science (Journal)
DENG, Z. (Reviewer)
5 Apr 2026Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Molecular Neurobiology (Journal)
DENG, Z. (Reviewer)
6 Jan 2026Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Journal of Integrative Neuroscience (Journal)
DENG, Z. (Reviewer)
19 Jan 2026Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Autophagy (Journal)
DENG, Z. (Reviewer)
13 May 2026Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)