Projects per year
Search results
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Active
Targeting osteoblastic 11β-HSD1 to combat high fat diet-induced bone loss, glucose handing impairment and obesity
LIU, J. (PI), WONG, H. L. X. (CoI), ZHANG, G. (CoI) & Wang, S. (CoI)
1/01/25 → 31/12/27
Project: Research project
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Osteoblastic sclerostin loop3-LRP4 interaction could be required by sclerostin to inhibit bone formation
ZHANG, G. (PI) & WANG, L. (CoI)
1/01/25 → 31/12/27
Project: Research project
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Development of Small-molecule Inhibitors Targeting Sclerostin Loop3 for Osteoporosis
ZHANG, G. (PI)
23/08/24 → 31/03/25
Project: Research project
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Development of Small-molecule Inhibitors Targeting Sclerostin Loop3 for Osteoporosis
ZHANG, G. (PI)
25/09/23 → 31/03/25
Project: Research project
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Development of Small-molecule Inhibitors Targeting Sclerostin Loop3 for Osteoporosis
ZHANG, G. (PI) & WANG, L. (CoPI)
1/04/23 → 31/03/25
Project: Research project
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Not started
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Study on molecular mechanism of bone formation reduction in aged women: functional role of CKIP-1
ZHANG, G. (PI)
Project: Research project
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Aptamer: Molecular Insight & Translational Theranostics
LYU, A. (PI), ZHANG, G. (CoPI), REN, K. (CoPI) & Tan, W. (CoPI)
Project: Research project
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Finished
Development of Small-molecule Inhibitors Targeting Sclerostin Loop3 for Osteoporosis
ZHANG, G. (PI)
3/10/23 → 26/01/25
Project: Research project
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Development of Small-molecule Inhibitors Targeting Sclerostin Loop3 for Osteoporosis
ZHANG, G. (PI)
1/09/23 → 31/08/24
Project: Research project
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Effects of a novel Smurf1 inhibitor loaded in alginate hydrogel on local bone formation in distinctive age-related osteoporosis during spinal fusion
ZHANG, G. (PI), LIANG, C. (CoPI), LYU, A. (CoPI) & LU, J. (CoPI)
1/11/19 → 30/04/22
Project: Research project
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From precision medicine to drug discovery: osteoblast-specific inhibition of Smurf1 activity promotes bone formation in distinctive rats with age-related osteoporosis
ZHANG, G. (PI)
1/01/19 → 31/12/22
Project: Research project
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The role of osteoclastic miR-214-3p in early osteoarthritis development
ZHANG, G. (PI)
1/01/18 → 30/06/20
Project: Research project
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Role of osteoclast-derived exosomal miR-214 in regulating osteoblastic bone formation
ZHANG, G. (PI)
1/01/17 → 31/12/20
Project: Research project
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Targeting sclerostin to reverse established osteoporosis: Aptamer characterization and evaluation for drug discovery
ZHANG, G. (PI)
1/01/17 → 31/12/18
Project: Research project
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Aptamer-functionalized osteoblast-targeting delivery system for osteogenic siRNAs to achieve cell-specific RNA interference for bone anabolic therapy
ZHANG, G. (PI)
1/01/15 → 30/06/18
Project: Research project
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Toward a novel bone anabolic strategy for aged postmenopausal osteoporosis: Inhibiting miR-214 in osteogenic cells for promoting bone formation
ZHANG, G. (PI)
1/01/13 → 31/12/15
Project: Research project
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Skeletal Role of CK2-interating Protein-1 in Regulating Osteoblastic Bone Formation: Molecular Mechanism and Reversing Osteoporosis
ZHANG, G. (PI)
1/01/13 → 31/12/16
Project: Research project
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Therapeutic RNAi Targareting CKIP-1 to Reverse Severe Postmenopausal Osteoporosis
ZHANG, G. (PI)
1/01/12 → 30/09/14
Project: Research project