Yuanyuan YU, Prof

Associate Director, Institute of Integrated Bioinformedicine and Translational Science (IBTS)

Accepting PhD Students

PhD projects

Targeting sclerostin loop3 to promote bone formation with low cardiovascular risk in animal models
The role of the interactions between N domain and Linker 2 of DKK1 in modulating the immunosuppressive tumor microenvironment mediated by DKK1C domain
AI-powered aptamer drug discovery

20162025

Research activity per year

Personal profile

Chinese Name

于媛媛

Research Interests

1) Optimization of aptamer selection methodology;

2) Aptamer-based translational medicine and drug discovery;

3) Aptamer structural biology

研究興趣:

1)核酸適配體篩選方法優化;

2)基於核酸配適體的轉化醫學與藥物發現;

3)核酸適配體結構生物學

Biography

Prof. Yuanyuan Yu is a tenure track Assistant Professor in the School of Chinese Medicine. She earned her PhD in Biochemistry from Faculty of Medicine at the University of Hong Kong in 2015.  Prof. Yu has undertaken multiple external grants in the capacity of PI (such as GRF-RGC and NSFC). Prof. Yu has focused on developing therapeutic aptamers for various diseases.  Her research mainly focuses on aptamer-based drug discovery, including understanding disease mechanisms, identifying targets and discovering drug for diseases, particularly rare and geriatric diseases that lack specific treatments.

個人簡介:

于教授為中醫藥學院助理教授(終身職軌)。她於2015年在香港大學醫學院獲得生物化學博士學位。于教授以首席研究員(PI)身分主持多項外部研究資助(如研究資助局 RGC 的優配研究基金 GRF 及國家自然科學基金 NSFC)。于 教授致力於研發用於多種疾病的治療性核酸適配體。其研究主要聚焦於基於核酸適體的藥物發現,包括闡明疾病機制、鑑定靶點與發現/開發新藥,特別關注缺乏針對性治療的罕見疾病與老年性疾病。

任教科目:

微生物學、分子生物學及生物化學

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 9 - Industry, Innovation, and Infrastructure

Education/Academic qualification

PhD, The University of Hong Kong

1 Sept 201028 Feb 2015

Award Date: 21 Nov 2015

External positions

Guangdong‐Hong Kong Macao Greater Bay Area International Research Platform for Aptamer‐Based Translational Medicine and Drug Discovery

1 Jan 2017 → …

Keywords

  • QH301 Biology
  • Biochemistry
  • Molecular Biology
  • RM Therapeutics. Pharmacology
  • Drug Discovery
  • Aptamer

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Dive into the research topics where Yuanyuan YU is active. Topic labels come from the works of this scholar.
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Collaborations and top research areas from the last five years

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