Projects per year
Personal profile
Chinese Name
于媛媛
Research Interests
1) Optimization of aptamer selection methodology;
2) Aptamer-based translational medicine and drug discovery;
3) Aptamer structural biology
Biography
Dr. Yuanyuan Yu is a tenure track Assistant Professor in the School of Chinese Medicine. She earned her PhD in Biochemistry from Faculty of Medicine at the University of Hong Kong in 2015. After graduation, she joined the School of Chinese Medicine at Hong Kong Baptist University as a postdoctoral research fellow from 2015 to 2019. She was promoted to Research Assistant Professor in 2019 and Assistant Professor in 2022. Dr. Yu has undertaken multiple external grants in the capacity of PI (such as GRF-RGC and NSFC). Dr. Yu has focused on developing therapeutic aptamers for various diseases. Her research mainly focuses on aptamer-based drug discovery, including understanding disease mechanisms, identifying targets and discovering drug for diseases, particularly rare and geriatric diseasesthat lack specific treatments.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, The University of Hong Kong
1 Sept 2010 → 28 Feb 2015
Award Date: 21 Nov 2015
External positions
Guangdong‐Hong Kong Macao Greater Bay Area International Research Platform for Aptamer‐Based Translational Medicine and Drug Discovery
1 Jan 2017 → …
Keywords
- QH301 Biology
- Biochemistry
- Molecular Biology
- RM Therapeutics. Pharmacology
- Drug Discovery
- Aptamer
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Dive into the research topics where Yuanyuan YU is active. Topic labels come from the works of this scholar.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Targeting sclerostin loop3 to promote bone formation with low cardiovascular risk in animal models
1/01/21 → 31/12/23
Project: Research project
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Development of a Real-Time TaqMan RT-PCR Assay for the Detection of NADC34-like Porcine Reproductive and Respiratory Syndrome Virus
Tu, T., Pang, M., Jiang, D., Zhou, Y., Wu, X., Yao, X., Luo, Y., Yang, Z., Ren, M., Lu, A., Zhang, G., Yu, Y. & Wang, Y., 6 Apr 2023, In: Veterinary Sciences. 10, 4, 11 p., 279.Research output: Contribution to journal › Journal article › peer-review
Open Access -
Editorial: Aptamer-based structural biology, computational modelling, translational research and drug discovery, Volume II
Ma, Y., Yu, Y., Zhang, B., Lu, A. & Zhang, G., 15 May 2023, In: Frontiers in Cell and Developmental Biology. 11, 2 p., 1195372.Research output: Contribution to journal › Editorial
Open Access -
Exploring the Potential of Aptamers in Targeting Neuroinflammation and Neurodegenerative Disorders: Opportunities and Challenges
Kong, A. H. Y., Wu, A. J., Ho, O. K. Y., Leung, M. M. K., Huang, A. S., Yu, Y., Zhang, G., Lyu, A., Li, M. & Cheung, K. H., 2 Jul 2023, In: International Journal of Molecular Sciences. 24, 14, 33 p., 11780.Research output: Contribution to journal › Review article › peer-review
Open Access -
Macrophagic Sclerostin Loop2-ApoER2 Interaction Required by Sclerostin for Suppressing Inflammatory Responses (Abstract)
Wang, L., Zhang, N., Liu, J., Yang, X., Yu, Y., Li, D., Jiang, H., Sun, M., Li, N., Ma, D., Huang, Y., Lu, A., Zhang, B. & Zhang, G., May 2023, In: Metabolism: Clinical and Experimental. 142, Supplement, p. 155427 1 p.Research output: Contribution to journal › Conference article › peer-review
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Pan-genome wide association study of Glaesserella parasuis highlights genes associated with virulence and biofilm formation
Zhou, Y., Jiang, D., Yao, X., Luo, Y., Yang, Z., Ren, M., Zhang, G., Yu, Y., Lu, A. & Wang, Y., 17 Apr 2023, In: Frontiers in Microbiology. 14, 22 p., 1160433.Research output: Contribution to journal › Journal article › peer-review
Open Access
Prizes
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2023 Geneva international inventions: silver prize
MA, Yuan (Recipient) & YU, Yuanyuan (Recipient), 29 Apr 2023
Prize
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An aptamer drug targeting sclerostin loop3 for bone anabolic therapy without increasing cardiovascular risk
YU, Yuanyuan (Recipient), Apr 2023
Prize: Award
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First runner-up, Best Poster Award, The Blue Sky Research Fund Open Forum, HKBU
YU, Yuanyuan (Recipient), 2022
Prize: Award
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Activities
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Expert Opinion on Drug Discovery (Journal)
Yuanyuan YU (Reviewer)
1 Mar 2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Alleviating Microgravity-induced Bone Loss in Astronauts During Deep Space Exploration
Yuanyuan YU (Participant), Ge ZHANG (Participant) & Aiping LYU (Organiser)
22 Oct 2022 → 30 Oct 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Aptamer-based Translational Medicine and Drug Discovery
Yuanyuan YU (Participant)
12 Dec 2022 → 22 Dec 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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Aptamer
Yuanyuan YU (Participant)
10 Nov 2022 → 11 Nov 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
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AI and Drug Discovery
Yuanyuan YU (Session chair)
13 Aug 2022Activity: Conference/talk/lecture/symposium/speech/workshop, etc › Event organized by non-HKBU units
Press/Media
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From Molecular Target to Aptamer Drug Discovery towards US-FDA Orphan Drug Designation
Yuanyuan YU, Ge ZHANG, Aiping LYU & Luyao WANG
19/12/22 → 20/12/22
4 Media contributions
Press/Media