Projects per year
Personal profile
Chinese Name
Research Interests
Biomolecular modeling and QSPR
Biography
After graduated from CUHK with a BSc in Chemistry, I was trained in USA as a computational chemist in the early 90s under the supervision of Prof. B. M. Pettitt focusing on the biomolecular structures and energetics of DNA triple helices. My interests in applying physical principles to biomolecules was further enhanced during my postdoctorate at UT Austin (USA) with Prof. P. J. Rossky on investigating the hydration structures of membrane proteins. When came back to Hong Kong at HKBU til to date, I continued in broadening my exploration in computatonal chemistry to touch on various interdiscplinary topics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Network
Projects
- 2 Finished
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Comparative Binding Studies of Steroids and Novel Ligands of Pharmacological Values to the Glucocorticoid Receptors
1/01/08 → 30/06/11
Project: Research project
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Modeling of Polysaccharide-based Chiral Stationary Phase for Enantioseparation by Computational and Experimental Approaches
1/10/04 → 31/03/08
Project: Research project
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(4 + 3) cycloadditions of allenyl ether-derived oxygen-stabilized oxyallyls with furans
Huang, X., Thor, W., Feng, X., Kang, L., Yang, M., LEE, C. S., CHENG, Y. K. & He, S., 21 Jan 2020, In: Organic Chemistry Frontiers. 7, 2, p. 255-260 6 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Construction of cyclopenta[: B] pyran-2-ones via chemoselective (3 + 2) cycloaddition between 2-pyrones and vinyl cyclopropanes
Liang, X., Ye, W., Thor, W., Sun, L., Wang, B., He, S., CHENG, Y. K. & LEE, C. S., 21 Mar 2020, In: Organic Chemistry Frontiers. 7, 6, p. 840-845 6 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Synthesis of the Tricyclic Picrotoxane Motif by an Oxidative Cascade Cyclization
Cao, J., Thor, W., Yang, S., Zhang, M., Bao, W., Zhu, L., Yang, W., Cheng, Y. K. & Lee, C. S., 21 Jun 2019, In: Organic Letters. 21, 12, p. 4896-4899 4 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Ginsenoside Rg3 stereoisomers differentially inhibit vascular smooth muscle cell proliferation and migration in diabetic atherosclerosis
Guo, M., Guo, G., Xiao, J., Sheng, X., Zhang, X., Tie, Y., CHENG, Y. K. & Ji, X., Jun 2018, In: Journal of Cellular and Molecular Medicine. 22, 6, p. 3202-3214 13 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus) -
Identification of novel phosphodiesterase-4D inhibitors prescreened by molecular dynamics-augmented modeling and validated by bioassay
Li, Z., Cai, Y. H., CHENG, Y. K., Lu, X., Shao, Y. X., Li, X., Liu, M., Liu, P. & Luo, H. B., 22 Apr 2013, In: Journal of Chemical Information and Modeling. 53, 4, p. 972-981 10 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus)