Projects per year
Personal profile
Chinese Name
Biography
Xiangze Zeng is currently an Assistant Professor in the physics department with an affiliated position in the School of Chinese Medicine at Hong Kong Baptist University. He obtained his BSc in physics at Shandong University in 2013. Then he did his PhD study in the chemistry department at Hong Kong University of Science and Technology from 2013 to 2017. After that, he got postdoc training at Washington University in St. Louis.
Xiangze is interested in studying the kinetics and thermodynamics of biomolecules at the atomic and molecular level. He aims to uncover the molecular mechanism of different molecular processes, using computer simulations (all-atom and coarse-grained simulations), mathematical modelling, and close collaborations with experimentalists.
Research Interests
Computational biophysics
Intrinsically disordered proteins
Phase separation in biology
Protein-protein/ligand interactions
Molecular dynamics and Monte Carlo simulations
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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The 6th Symposium on Biophysics Postgraduate Research in Hong Kong
ZENG, X. (PI)
6/01/24 → 6/01/24
Project: Research project
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Backbone-mediated weakening of pairwise interactions enables percolation in peptide-based mimics of protein condensates
Zeng, X. & Pappu, R. V., 6 Apr 2025, In: Communications Chemistry. 8, 1, 14 p., 106.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Phenomenological Model for the Efficient General Regulatory Role of Metabolites
Wu, X., Chen, L., Hu, G., Ou, X., Zeng, X., Shi, R. & Li, J., 17 Jul 2025, In: Journal of Physical Chemistry B. 129, 28, p. 7079-7087 9 p.Research output: Contribution to journal › Journal article › peer-review
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Recent advances in the synthesis and application of biomolecular condensates
Li, Z., Tan, W., Zhao, G.-P., Zeng, X. & Zhao, W., Feb 2025, In: Journal of Biological Chemistry. 301, 2, 14 p., 108188.Research output: Contribution to journal › Journal article › peer-review
Open Access1 Citation (Scopus) -
Staudinger Reaction-Responsive Coacervates for Cytosolic Antibody Delivery and TRIM21-Mediated Protein Degradation
Bao, Y., Xu, Z., Cheng, K., Li, X., Chen, F., Yuan, D., Zhang, F., Che, A.R.-Y., Zeng, X., Zhao, Y.-D. & Xia, J., 29 Jan 2025, In: Journal of the American Chemical Society. 147, 4, p. 3830-3839 10 p.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
Cell Surface Engineering by Phase-Separated Coacervates for Antibody Display and Targeted Cancer Cell Therapy
Chen, H., Bao, Y., Li, X., Chen, F., Sugimura, R., Zeng, X. & Xia, J., 24 Oct 2024, In: Angewandte Chemie - International Edition. 63, 44, 9 p., e202410566.Research output: Contribution to journal › Journal article › peer-review
Open Access17 Citations (Scopus)
Activities
- 3 Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Journal of Chemical Information and Modeling (Journal)
ZENG, X. (Reviewer)
1 Nov 2025 → 31 Dec 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Biophysical Journal (Journal)
ZENG, X. (Reviewer)
1 Mar 2025 → 30 Jun 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Journal of the American Chemical Society (Journal)
ZENG, X. (Reviewer)
1 Nov 2024 → 31 Dec 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)