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Xiangze Zeng is currently an Assistant Professor in the physics department with an affiliated position in the School of Chinese Medicine at Hong Kong Baptist University. He obtained his BSc in physics at Shandong University in 2013. Then he did his PhD study in the chemistry department at Hong Kong University of Science and Technology from 2013 to 2017. After that, he got postdoc training at Washington University in St. Louis.
Xiangze is interested in studying the kinetics and thermodynamics of biomolecules at the atomic and molecular level. He aims to uncover the molecular mechanism of different molecular processes, using computer simulations (all-atom and coarse-grained simulations), mathematical modelling, and close collaborations with experimentalists.
Intrinsically disordered proteins
Phase separation in biology
Molecular dynamics and Monte Carlo simulations
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Zeng, X. & Pappu, R. V., Apr 2023, In: Current Opinion in Structural Biology. 79, 10 p., 102540.
Research output: Contribution to journal › Journal article › peer-reviewOpen Access3 Citations (Scopus)
Farag, M., Holehouse, A. S., Zeng, X. & Pappu, R. V., 20 Jun 2023, In: Biophysical Journal. 122, 12, p. 2396-2403 8 p.
Research output: Contribution to journal › Journal article › peer-review1 Citation (Scopus)
Dai, Y., Farag, M., Lee, D., Zeng, X., Kim, K., Son, H. I., Guo, X., Su, J., Peterson, N., Mohammed, J., Ney, M., Shapiro, D. M., Pappu, R. V., Chilkoti, A. & You, L., Apr 2023, In: Nature Chemical Biology. 19, 4, p. 518-528 11 p.
Research output: Contribution to journal › Journal article › peer-review8 Citations (Scopus)
Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteinsZeng, X., Ruff, K. M. & Pappu, R. V., 10 May 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 19, 10 p., e2200559119.
Research output: Contribution to journal › Journal article › peer-reviewOpen Access20 Citations (Scopus)
Design of intrinsically disordered proteins that undergo phase transitions with lower critical solution temperaturesZeng, X., Liu, C., Fossat, M. J., Ren, P., Chilkoti, A. & Pappu, R. V., Feb 2021, In: APL Materials. 9, 2, 13 p., 021119.
Research output: Contribution to journal › Journal article › peer-reviewOpen Access17 Citations (Scopus)