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Personal profile
Chinese Name
曾祥澤
Biography
Xiangze Zeng is currently an Assistant Professor in the physics department with an affiliated position in the School of Chinese Medicine at Hong Kong Baptist University. He obtained his BSc in physics at Shandong University in 2013. Then he did his PhD study in the chemistry department at Hong Kong University of Science and Technology from 2013 to 2017. After that, he got postdoc training at Washington University in St. Louis.
Xiangze is interested in studying the kinetics and thermodynamics of biomolecules at the atomic and molecular level. He aims to uncover the molecular mechanism of different molecular processes, using computer simulations (all-atom and coarse-grained simulations), mathematical modelling, and close collaborations with experimentalists.
Research Interests
Computational biophysics
Intrinsically disordered proteins
Phase separation in biology
Protein-protein/ligand interactions
Molecular dynamics and Monte Carlo simulations
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Xiangze ZENG is active. Topic labels come from the works of this scholar.
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Projects
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Developments in describing equilibrium phase transitions of multivalent associative macromolecules
Zeng, X. & Pappu, R. V., Apr 2023, In: Current Opinion in Structural Biology. 79, 10 p., 102540.Research output: Contribution to journal › Journal article › peer-review
Open Access3 Citations (Scopus) -
FIREBALL: A tool to fit protein phase diagrams based on mean-field theories for polymer solutions
Farag, M., Holehouse, A. S., Zeng, X. & Pappu, R. V., 20 Jun 2023, In: Biophysical Journal. 122, 12, p. 2396-2403 8 p.Research output: Contribution to journal › Journal article › peer-review
1 Citation (Scopus) -
Programmable synthetic biomolecular condensates for cellular control
Dai, Y., Farag, M., Lee, D., Zeng, X., Kim, K., Son, H. I., Guo, X., Su, J., Peterson, N., Mohammed, J., Ney, M., Shapiro, D. M., Pappu, R. V., Chilkoti, A. & You, L., Apr 2023, In: Nature Chemical Biology. 19, 4, p. 518-528 11 p.Research output: Contribution to journal › Journal article › peer-review
8 Citations (Scopus) -
Competing interactions give rise to two-state behavior and switch-like transitions in charge-rich intrinsically disordered proteins
Zeng, X., Ruff, K. M. & Pappu, R. V., 10 May 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 19, 10 p., e2200559119.Research output: Contribution to journal › Journal article › peer-review
Open Access20 Citations (Scopus) -
Design of intrinsically disordered proteins that undergo phase transitions with lower critical solution temperatures
Zeng, X., Liu, C., Fossat, M. J., Ren, P., Chilkoti, A. & Pappu, R. V., Feb 2021, In: APL Materials. 9, 2, 13 p., 021119.Research output: Contribution to journal › Journal article › peer-review
Open Access17 Citations (Scopus)