Projects per year
Personal profile
Chinese Name
王凱亮
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, Department of Biochemistry, The University of Hong Kong
Award Date: 1 Oct 2013
Bachelor, Biochemistry & Biotechnology, School of Biological Sciences, Faculty of Science, The University of Hong Kong
Award Date: 1 Oct 2009
Keywords
- QP Physiology
- Cell Metabolism
- Cell signaling
- RB Pathology
- diabetes
- obesity
- QR180 Immunology
- Microbiome
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Dive into the research topics where Hoi Leong Xavier WONG is active. Topic labels come from the works of this scholar.
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Investigating the role of ADAM9 in the regulation of body weight and food intake
3/01/22 → 2/01/25
Project: Research project
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To investigate the role of klotho shedding in the ageing process
1/01/21 → 31/12/23
Project: Research project
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Investigating the role of MT1-MMP in the regulation of insulin sensitivity and the therapeutic potential of MT1-MMP inhibition in Type 2 diabetes mellitus
1/07/19 → 30/06/22
Project: Research project
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Regulation of age-associated insulin resistance by MT1-MMP-mediated cleavage of insulin receptor
Guo, X., Asthana, P., Gurung, S., Zhang, S., Wong, S. K. K., Fallah, S., Chow, C. F. W., Che, S., Zhai, L., Wang, Z., Ge, X., Jiang, Z., Wu, J., Zhang, Y., Wu, X., Xu, K., Lin, C. Y., Kwan, H. Y., Lyu, A., Zhou, Z., & 2 others, 29 Jun 2022, In: Nature Communications. 13, 1, 10 p., 3749.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Body weight regulation via MT1-MMP-mediated cleavage of GFRAL
Chow, C. F. W., Guo, X., Asthana, P., Zhang, S., Wong, S. K. K., Fallah, S., Che, S., Gurung, S., Wang, Z., Lee, K. B., Ge, X., Yuan, S., Xu, H., Ip, J. P. K., Jiang, Z., Zhai, L., Wu, J., Zhang, Y., Mahato, A. K., Saarma, M., & 7 others, 17 Feb 2022, In: Nature Metabolism. 4, 2, p. 203–212 10 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Ruminococcus gnavus plays a pathogenic role in diarrhea-predominant irritable bowel syndrome by increasing serotonin biosynthesis
Zhai, L., Huang, C., Ning, Z., Zhang, Y., Zhuang, M., Yang, W., Wang, X., Wang, J., Zhang, L., Xiao, H., Zhao, L., Asthana, P., Lam, Y. Y., Chow, C. F. W., Huang, J. D., Yuan, S., Chan, K. M., Yuan, C. S., Lau, J. Y. N., Wong, H. L. X., & 1 others, 11 Jan 2023, In: Cell Host and Microbe. 31, 1, p. 33-44.e5 12 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2
Guo, X., Cao, J., Cai, J. P., Wu, J., Huang, J., Asthana, P., Wong, S. K. K., Ye, Z. W., Gurung, S., Zhang, Y., Wang, S., Wang, Z., Ge, X., Kwan, H. Y., Lyu, A., Chan, K. M., Wong, N., Huang, J., Zhou, Z., Bian, Z. X., & 2 others, 23 Dec 2022, In: Nature Communications. 13, 17 p., 7907.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Early life stress disrupts intestinal homeostasis via NGF-TrkA signaling
Wong, H. L. X., Qin, H. Y., Tsang, S. W., Zuo, X., Che, S., Chow, C. F. W., Li, X., Xiao, H. T., Zhao, L., Huang, T., Lin, C. Y., Kwan, H. Y., Yang, T., Longo, F. M., Lyu, A. & Bian, Z. X., Dec 2019, In: Nature Communications. 10, 1745.Research output: Contribution to journal › Article › peer-review
Open Access30 Citations (Scopus)
Prizes
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President's Award for Outstanding Performance as Early Career Researcher
WONG, Hoi Leong Xavier (Recipient), 2022
Prize: Award
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Activities
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Metabolites (Journal)
Hoi Leong Xavier WONG (Reviewer)
2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Journal of Cell Science (Journal)
Hoi Leong Xavier WONG (Reviewer)
2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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International Journal of Molecular Sciences (Journal)
Hoi Leong Xavier WONG (Reviewer)
2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Nutrients (Journal)
Hoi Leong Xavier WONG (Reviewer)
2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Pharmaceuticals (Journal)
Hoi Leong Xavier WONG (Reviewer)
2023Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)