Projects per year
Personal profile
Chinese Name
Chinese Name
Biography
Dr. Chan is a Research Assistant Professor in the School of Chinese Medicine at Hong Kong Baptist University (HKBU). He received his PhD from The Chinese University of Hong Kong (CUHK) in 2022. As an accomplished investigator, Dr. Chan has published 29 SCI-indexed papers with a cumulative Impact Factor exceeding 260, including 9 as first author and 2 as corresponding author. His high-impact research includes prominent first-author publications in prestigious journals such as Science Immunology and Autophagy, as well as co-corresponding author work in the Journal of Translational Medicine.
Dr. Chan’s research program bridges translational and mechanistic approaches to investigate the systemic drivers of inflammatory skin disorders. His current work focuses on the interactions between psychological stress-associated fibroblasts and the microbiota during disease onset, progression, and prevention. By mapping the intricate crosstalk among stress hormones, microbial ecology, and immunity, his research aims to establish clear causal mechanisms that advance the field of preventative dermatology.
Reserach Interests
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Fibroblast-Mediated Immunoregulation in Skin Disorders: Investigating how dermal fibroblasts actively modulate immune responses and contribute to the pathogenesis of inflammatory skin conditions.
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Host-Microbiota Interactions in Inflammatory Diseases: Exploring the complex crosstalk between host immunity and microbial ecology to uncover systemic drivers of inflammation.
Keywords
- RL Dermatology
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Collaborations and top research areas from the last five years
Projects
- 1 Not started
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Elucidating the genotoxicity of Fusobacterium nucleatum-secreted mutagens in colorectal cancer carcinogenesis
Xu, W., Zhang, Y., Chen, D., Huang, D., Zhao, Y., Hu, W., Lin, L., Liu, Y., Wang, S., Zeng, J., Xie, C., Chan, H., Li, Q., Chen, H., Liu, X., Wong, S. H., Yu, J., Chan, F. K. L., Chan, M. T. V. & Ng, S. C. & 2 others, , Dec 2024, In: Gut Pathogens. 16, 1, 13 p., 50.Research output: Contribution to journal › Journal article › peer-review
Open Access10 Citations (Scopus) -
LOX-1 acts as an N6-methyladenosine-regulated receptor for Helicobacter pylori by binding to the bacterial catalase
Zeng, J., Xie, C., Huang, Z., Cho, C. H., Chan, H., Li, Q., Ashktorab, H., Smoot, D. T., Wong, S. H., Yu, J., Gong, W., Liang, C., Xu, H., Chen, H., Liu, X., Wu, J. C. Y., Ip, M., Gin, T., Zhang, L. & Chan, M. T. V. & 2 others, , 22 Jan 2024, In: Nature Communications. 15, 1, 17 p., 669.Research output: Contribution to journal › Journal article › peer-review
Open Access22 Citations (Scopus) -
Carnobacterium maltaromaticum boosts intestinal vitamin D production to suppress colorectal cancer in female mice
Li, Q., Chan, H., Liu, W. X., Liu, C. A., Zhou, Y., Huang, D., Wang, X., Li, X., Xie, C., Liu, W. Y. Z., Wang, X. S., Ng, S. K., Gou, H., Zhao, L. Y., Fong, W., Jiang, L., Lin, Y., Zhao, G., Bai, F. & Liu, X. & 6 others, , 14 Aug 2023, In: Cancer Cell. 41, 8, p. 1450-1465.e8 25 p.Research output: Contribution to journal › Journal article › peer-review
Open Access109 Citations (Scopus) -
Immune dysregulation and RNA N6-methyladenosine modification in sepsis
Chen, H., Zhang, X., Su, H., Zeng, J., Chan, H., Li, Q., Liu, X., Zhang, L., Wu, W. K. K., Chan, M. T. V. & Chen, H., 1 May 2023, In: Wiley Interdisciplinary Reviews: RNA. 14, 3, e1764.Research output: Contribution to journal › Journal article › peer-review
27 Citations (Scopus) -
SARS-CoV-2 non-structural protein 6 triggers NLRP3-dependent pyroptosis by targeting ATP6AP1
Sun, X., Liu, Y., Huang, Z., Xu, W., Hu, W., Yi, L., Liu, Z., Chan, H., Zeng, J., Liu, X., Chen, H., Yu, J., Chan, F. K. L., Ng, S. C., Wong, S. H., Wang, M. H., Gin, T., Joynt, G. M., Hui, D. S. C. & Zou, X. & 8 others, , Jun 2022, In: Cell Death and Differentiation. 29, 6, p. 1240-1254 15 p.Research output: Contribution to journal › Journal article › peer-review
Open Access158 Citations (Scopus)
Activities
- 1 Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Journal of Translational Medicine (Journal)
CHAN, H. (Reviewer)
Jul 2026Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)