Projects per year
Personal profile
Chinese Name
Biography
Dr. Liu graduated with B.Med. and M.Med. degrees in Sun Yat-sen University in 2010 and 2013, respectively, and then received his Ph.D. degree from Hong Kong Baptist University in 2016. He then finished his postdoctoral training and served as a Research Assistant Professor in Law Sau Fai Institute for Advancing Translational Medicine in Bone & Joint Diseases (TMBJ), HKBU. He became a tenure-track Assistant Professor in School of Chinese Medicine at HKBU in September 2021,and an Associate Professor with tenure in July 2025.
劉進博士2010年本科畢業於中山大學中山醫學院臨床醫學系,2013年獲中山大學醫學碩士學位,2016年獲香港浸會大學生物醫學哲學博士學位,先後在香港浸會大學羅守輝骨與關節疾病轉化醫學研究所擔任博士後研究員和研究助理教授,2021年9月起擔任香港浸會大學中醫藥學院助理教授,2025年7月晉升為副教授。
劉博士的研究興趣主要集中在:內源性糖皮質激素和外泌體介導的細胞間通訊参与调控肌肉骨骼系統疾病和腫瘤進程的分子機制與藥物發現,以及基於適配子的骨靶向藥物遞送研究。研究成果發表在Nature Aging, Nature Communications, Biomaterials, EBioMedicine, Aging Cells等國際知名學術期刊。
Research Interests
Innovative drug discovery in musculoskeletal diseases and cancer, with particular interest in the mechanistic understanding of how endogenous glucocorticoid signaling and extracellular vesicle-mediated intercellular communication contribute to bone and joint diseases and tumor microenviroment, and aptamer-based bone/tumor-targeting drug delivery as a therapeutic approach.
We are recruiting postgraduate students, post-doctoral research fellows and research assistant professors with the academic backgrounds and track records of bioinformatics, medicinal chemistry and chemical biology. 團隊現正招募生物信息學、藥物化學和化學生物學背景的研究生、博士後和研究助理教授。
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Collaborations and top research areas from the last five years
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Targeting osteoblastic 11β-HSD1 to combat high fat diet-induced bone loss, glucose handing impairment and obesity
LIU, J. (PI), WONG, H. L. X. (CoI), ZHANG, G. (CoI) & Wang, S. (CoI)
1/01/25 → 31/12/27
Project: Research project
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Equipment Matching Fund - High-performance Slide Scanner
LIU, J. (PI), LI, F. (CoI), YU, Y. (CoI), XU, J. (CoI), FU, X. (CoI), WONG, H. L. X. (CoI), KWAN, H. Y. (CoI) & CHONG, W. P. (CoI)
26/03/24 → 25/03/26
Project: Research project
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Equipment Matching Fund - Flow Nano Analyzer
LIU, J. (PI) & KWAN, H. Y. (CoI)
26/03/24 → 25/03/26
Project: Research project
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Blocking exosome release from atrophic skeletal muscle to strengthen bone: a novel therapeutic strategy for muscle atrophy-associated bone loss?
LIU, J. (PI)
1/09/23 → 31/08/26
Project: Research project
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Macrophagic Sclerostin Loop2-ApoER2 Interaction Required by Sclerostin for Cardiovascular Protective Action
Wang, L., Tao, X., Zhang, N., Yang, X., Jiang, H., Li, X., Wang, S., Ding, S., Yu, S., Zhang, H., Zhang, Y., Li, N., Li, H., Li, Z., Wen, X., Sun, M., Zhong, C., Liu, J., Yu, Y. & Luo, X. & 8 others, , 9 Feb 2026, In: Advanced Science. 13, 8, 23 p., e18735.Research output: Contribution to journal › Journal article › peer-review
Open Access -
A Novel Exosome Inhibit or Limits Tumor Growth in Mice with Melanoma (B16F10) Allograft
LI, Z., GUAN, H., CHAN, W. H., WEN, X., LI, N., DENG, K., ZHONG, C., Lu, J., Lu, A. & LIU, J., 18 Jun 2025.Research output: Contribution to conference › Conference poster › peer-review
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Aptamer-engineered multivalent camptothecin conjugates synergistically orchestrate immunosuppressive microenvironment and DNA damage cascades in colorectal carcinoma
Zuo, Y., Yang, J., Wang, C., Wang, M., Chen, Y., Liu, J., Fang, Y., Chen, H., Sun, C., Zhou, X., Zhang, T., Deng, Y., Lu, A., Zheng, C., Chen, S. & Lu, J., 1 Dec 2025, In: Chemical Engineering Journal. 525, 18 p., 170036.Research output: Contribution to journal › Journal article › peer-review
2 Citations (Scopus) -
DeepAptamer: Advancing high-affinity aptamer discovery with a hybrid deep learning model
Yang, X., Chan, C. H., Yao, S., Chu, H. Y., Lyu, M., Chen, Z., Xiao, H., Ma, Y., Yu, S., Li, F., Liu, J., Wang, L., Zhang, Z., Zhang, B. T., Zhang, L., Lu, A., Wang, Y., Zhang, G. & Yu, Y., 11 Mar 2025, In: Molecular Therapy Nucleic Acids. 36, 1, 15 p., 102436.Research output: Contribution to journal › Journal article › peer-review
Open Access20 Citations (Scopus) -
Engineering selective PI3Kγ inhibitors with antitumor and immunomodulatory potentials
Zuo, Y. (Co-first author), Pu, Y. (Co-first author), Liu, J. (Co-first author), Chen, H. (Co-first author), Chen, Y., Li, X., Wang, Y., Zhang, T., Cheng, H., Liu, J., Deng, Y., Cong, Z., Wang, M., Lu, J. & Chen, S., 13 Nov 2025, (E-pub ahead of print) In: Acta Pharmaceutica Sinica B. 20 p.Research output: Contribution to journal › Journal article › peer-review
Open Access
Prizes
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School of Chinese Medicine Performance Award in Scholarly Work (Early Career Researcher)
LIU, J. (Recipient), 3 May 2023
Prize: Award
Activities
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Phytomedicine (Journal)
LIU, J. (Reviewer)
9 Mar 2025 → 22 Mar 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Pharmacological Research - Modern Chinese Medicine (Journal)
LIU, J. (Reviewer)
3 Mar 2025 → 13 Mar 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Bioactive Materials (Journal)
LIU, J. (Reviewer)
14 Apr 2025 → 1 May 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Frontiers in Bioengineering and Biotechnology (Journal)
LIU, J. (Guest editor)
1 Jan 2025 → 30 Jun 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
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Materials Today Bio (Journal)
LIU, J. (Reviewer)
9 Feb 2025 → 25 Feb 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)