Projects per year
Personal profile
Chinese Name
Biography
Dr. Liu graduated with B.Med. and M.Med. degrees in Sun Yat-sen University in 2010 and 2013, respectively, and then received his Ph.D. degree from Hong Kong Baptist University in 2016. He then finished his postdoctoral training and served as a Research Assistant Professor in Law Sau Fai Institute for Advancing Translational Medicine in Bone & Joint Diseases (TMBJ), HKBU. He became a tenure-track Assistant Professor in School of Chinese Medicine at HKBU in September 2021,and an Associate Professor with tenure in July 2025.
劉進博士2010年本科畢業於中山大學中山醫學院臨床醫學系,2013年獲中山大學醫學碩士學位,2016年獲香港浸會大學生物醫學哲學博士學位,先後在香港浸會大學羅守輝骨與關節疾病轉化醫學研究所擔任博士後研究員和研究助理教授,2021年9月起擔任香港浸會大學中醫藥學院助理教授,2025年7月晉升為副教授。
劉博士的研究興趣主要集中在:內源性糖皮質激素和外泌體介導的細胞間通訊参与调控肌肉骨骼系統疾病和腫瘤進程的分子機制與藥物發現,以及基於適配子的骨靶向藥物遞送研究。研究成果發表在Nature Aging, Nature Communications, Biomaterials, EBioMedicine, Aging Cells等國際知名學術期刊。
Research Interests
Innovative drug discovery in musculoskeletal diseases and cancer, with particular interest in the mechanistic understanding of how endogenous glucocorticoid signaling and extracellular vesicle-mediated intercellular communication contribute to bone and joint diseases and tumor microenviroment, and aptamer-based bone/tumor-targeting drug delivery as a therapeutic approach.
We are recruiting postgraduate students, post-doctoral research fellows and research assistant professors with the academic backgrounds and track records of bioinformatics, medicinal chemistry and chemical biology. 團隊現正招募生物信息學、藥物化學和化學生物學背景的研究生、博士後和研究助理教授。
Fingerprint
- 1 Similar Scholars
Collaborations and top research areas from the last five years
-
Targeting osteoblastic 11β-HSD1 to combat high fat diet-induced bone loss, glucose handing impairment and obesity
LIU, J. (PI), WONG, H. L. X. (CoI), ZHANG, G. (CoI) & Wang, S. (CoI)
1/01/25 → 31/12/27
Project: Research project
-
Equipment Matching Fund - Flow Nano Analyzer
LIU, J. (PI) & KWAN, H. Y. (CoI)
26/03/24 → 25/03/26
Project: Research project
-
Equipment Matching Fund - High-performance Slide Scanner
LIU, J. (PI), LI, F. (CoI), YU, Y. (CoI), XU, J. (CoI), FU, X. (CoI), WONG, H. L. X. (CoI), KWAN, H. Y. (CoI) & CHONG, W. P. (CoI)
26/03/24 → 25/03/26
Project: Research project
-
Blocking exosome release from atrophic skeletal muscle to strengthen bone: a novel therapeutic strategy for muscle atrophy-associated bone loss?
LIU, J. (PI)
1/09/23 → 31/08/26
Project: Research project
-
Adipocytic sclerostin loop3-LRP4 interaction required by sclerostin to impair whole-body lipid and glucose metabolism
Jiang, H. (Co-first author), Tao, X. (Co-first author), Yu, S. (Co-first author), Zhang, Y. (Co-first author), Ma, Y. (Co-first author), Li, N., Wang, S., Zhang, N., Yang, X., Ding, S., Zhong, C., Li, H., Li, Z., Wen, X., Zhang, H., Chen, Z., Sun, M., Luo, H., Ren, M. & Lei, C. & 9 others, , 16 Jan 2026, In: Nature Communications. 17, 18 p., 1812.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
Blocking interaction of sclerostin loop3 with osteoblastic LRP4 counteracts bone loss without increasing arterial stiffness during mechanical unloading
Wang, L., Zhang, N., Jiang, H., Tao, X., Ma, Y., Hu, Z., Zhong, C., Yang, X., Yu, S., Zhang, H., Liu, J., Yu, Y., Liu, F., Chen, Z., Luo, H., Ding, S., Zhang, Y., Sun, M., Zhang, S. & Ferdinandy, P. & 7 others, , Jul 2026, In: Journal of Orthopaedic Translation. 59, 13 p., 101117.Research output: Contribution to journal › Journal article › peer-review
Open Access2 Citations (Scopus) -
Design, synthesis, and biological evaluation of pyridine–triazole derivatives as URAT1 inhibitors with potential application in hyperuricemia and gout
Hu, Y., Liu, W., Sun, R., Li, M., Sun, S., Li, R., Zuo, Z., Liu, J., Zhou, L. & Wang, S., Jul 2026, In: Bioorganic and Medicinal Chemistry Letters. 136, 7 p., 130620.Research output: Contribution to journal › Journal article › peer-review
-
Design, synthesis, and Lead optimization of novel Quinazoline-based FLT3 inhibitors with potent anti-acute myelogenous leukemia activity
Liu, W., Du, S., Wang, M., Sun, S., Wang, L., Liu, J. & Wang, S., Jul 2026, In: Bioorganic and Medicinal Chemistry Letters. 136, 9 p., 130608.Research output: Contribution to journal › Journal article › peer-review
1 Citation (Scopus) -
Engineering selective PI3Kγ inhibitors with antitumor and immunomodulatory potentials
Zuo, Y. (Co-first author), Pu, Y. (Co-first author), Liu, J. (Co-first author), Chen, H. (Co-first author), Chen, Y., Li, X., Wang, Y., Zhang, T., Cheng, H., Liu, J., Deng, Y., Cong, Z., Wang, M., Lu, J. & Chen, S., Jul 2026, In: Acta Pharmaceutica Sinica B. 16, 7, p. 4083-4102 20 p.Research output: Contribution to journal › Journal article › peer-review
Open Access4 Citations (Scopus)
Prizes
-
-
-
-
-
School of Chinese Medicine Performance Award in Scholarly Work (Early Career Researcher)
LIU, J. (Recipient), 3 May 2023
Prize: Award
Activities
-
Biomedicine and Pharmacotherapy (Journal)
LIU, J. (Reviewer)
22 May 2026 → 8 Jun 2026Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
-
Journal of Orthopaedic Translation (Journal)
LIU, J. (Reviewer)
15 Jun 2026 → 29 Jun 2026Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
-
Phytomedicine (Journal)
LIU, J. (Reviewer)
4 Feb 2026 → 18 Feb 2026Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
-
Journal of Advanced Research (Journal)
LIU, J. (Reviewer)
2 Apr 2026 → 15 Apr 2026Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)
-
Materials Today Bio (Journal)
LIU, J. (Reviewer)
9 Feb 2025 → 25 Feb 2025Activity: Publication peer-review/editorial work › Editor/reviewer for publications (incl. CDCF T61 Journal Editor)